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Friday, August 4, 2023

Mirum Q2 update

  $37.5 million total revenue, including net product sales for LIVMARLI® (maralixibat) oral solution of $32.5 million, for second quarter 2023

- Acquiring CHENODAL® and CHOLBAM®, advancing Mirum’s leadership in pediatric hepatology with a multi-product franchise
- Four late-stage clinical trial data readouts expected later this year
- Conference call to provide business updates August 3 at 1:30 p.m. PT/4:30 p.m. ET

Mirum will host a conference call today, August 3, 2023, at 1:30 p.m. PT/4:30 p.m. ET, to provide business updates. Join the call using the following details:

Conference Call Details:

U.S./Toll-Free: +1 833 470 1428
International: +1 404 975 4839
Passcode: 969043

You may also access the call via webcast by visiting the Events & Presentations section on Mirum’s website. A replay of this webcast will be available for 30 days.

https://finance.yahoo.com/news/mirum-pharmaceuticals-reports-second-quarter-200500140.html

Dynavax ups revenue guidance

 

  • Generated record quarterly HEPLISAV-B® vaccine net product revenue of $56 million, a 73% year-over-year increase

  • Full year HEPLISAV-B net product revenue guidance raised to $200 - $215 million, compared to prior range of $165 - $185 million

  • Cash and investments increased to $682 million at quarter end; expects positive free cash flow for full year

  • Conference call Thursday at 4:30 p.m. ET/1:30 p.m. PT

2023 FINANCIAL GUIDANCE
Full year 2023 financial guidance has been revised to consist of the following expectations:

  • Raising HEPLISAV-B net product revenue between approximately $200 - $215 million, compared to the prior range of approximately $165 - $185 million

  • Reiterating research and development expenses between approximately $55 - $70 million

  • Reiterating selling, general and administrative expenses between approximately $135 - $155 million

Conference Call and Webcast Information

Dynavax will host a conference call and live audio webcast on Thursday, August 3, 2023, at 4:30 p.m. ET/1:30 p.m. PT. The live audio webcast may be accessed through the "Events & Presentations" page on the "Investors" section of the Company's website at https://investors.dynavax.com/events-presentations. A replay of the webcast will be available for 30 days following the live event.

To dial into the call, participants will need to register for the call using the caller registration link. It is recommended that participants dial into the conference call or log into the webcast approximately 10 minutes prior to the call.

https://finance.yahoo.com/news/dynavax-reports-second-quarter-2023-200500061.html

Alignment Healthcare Reports Second Quarter 2023 Results; Beats Outlook

 

  • Reports $462.4 million in total revenue, up 26.2% year-over-year

  • Medicare Advantage enrollment increases to approximately 112,200 members, up 17% year-over-year

 Alignment Healthcare, Inc. (NASDAQ: ALHC), a tech-enabled Medicare Advantage company, today reported financial results for its second quarter ended June 30, 2023.

“Our employees continue to deliver results by putting our members first, helping us to beat guidance across all four of our key metrics, including membership, revenue, adjusted gross profit and adjusted EBITDA,” said John Kao, founder and CEO. “We are making our mission of changing health care one person at a time a reality.”

Second Quarter 2023 Financial Highlights
All comparisons, unless otherwise noted, are to the three months ended June 30, 2022.

  • Health plan membership at the end of the quarter was approximately 112,200, up 17.0% year over year

  • Total revenue was $462.4 million, up 26.2% year over year

  • Health plan premium revenue of $424.7 million represented 21.0% growth year over year

  • Adjusted gross profit was $53.6 million and loss from operations was ($23.7) million

    • Adjusted gross profit excludes depreciation and amortization of $5.3 million and selling, general, and administrative expenses of $70.2 million (which includes $13.9 million of equity-based compensation). Adjusted gross profit also excludes an additional $1.8 million of equity-based compensation recorded within medical expenses

    • Medical benefits ratio based on adjusted gross profit was 88.4%

  • Adjusted EBITDA was ($2.1) million and net loss was ($28.5) million

OraSure Technologies (OSUR) Tops Q2 EPS by 16c, beats revenue views

 OraSure Technologies (NASDAQ: OSUR) reported Q2 EPS of $0.09, $0.16 better than the analyst estimate of ($0.07). Revenue for the quarter came in at $85.44 million versus the consensus estimate of $63.89 million.

https://www.streetinsider.com/Earnings/OraSure+Technologies+%28OSUR%29+Tops+Q2+EPS+by+16c%2C+beats+revenue/21995337.html

Russia says JPMorgan stops processing its grain payments

 U.S. bank JPMorgan this week stopped processing payments for the Russian Agricultural Bank, Russia said on Friday, as it demanded action, not promises, from Washington to help Russian grain and fertilizer reach global markets.

JPMorgan had handled some Russian grain export payments for the past few months with reassurances from Washington. However, that cooperation stopped this week, Russia's Foreign Ministry said on Friday.

"The direct channel between the Russian Agricultural Bank and JPMorgan ... was closed on Aug. 2," foreign ministry spokeswoman Maria Zakharova was quoted by Russian media as saying.

The United Nations, the U.S. State Department and JPMorgan declined to comment.

Moscow had allowed the safe export of Ukraine grain via the Black Sea for the past year under a deal it quit on July 17. Russia has a list of demands it wants met before it will return to the arrangement.

Under a related pact - also brokered in July 2022 - U.N. officials agreed to help Russian food and fertilizer exports reach global markets. "As soon as this is done, this deal will immediately be renewed," Kremlin spokesman Dmitry Peskov told reporters on Friday. A key Russian demand has been the reconnection of the Russian Agricultural Bank to the SWIFT international payments system. It was cut off by the European Union in June 2022 following Russia's invasion of Ukraine.

Zakharov, the foreign ministry spokeswoman, said the West and the United Nations "tried to present (payment processing by JPMorgan) as a working alternative to SWIFT."

U.S. Secretary of State Antony Blinken told reporters on Thursday that Washington would continue to do "whatever is necessary" to ensure Russia can freely export food if the Black Sea grain deal was revived.

While Russian exports of food and fertilizer are not subject to Western sanctions imposed after Russia's February 2022 invasion of Ukraine, Moscow has said restrictions on payments, logistics and insurance have hindered shipments.

US SAYS RUSSIA HAS STRONG EXPORTS

Top U.S. State Department sanctions official James O'Brien said on Friday that Russia needed to be clear about what it was asking for and what constituted success, suggesting it should be how much food and fertilizer reaches the world.

"It has put forth a number of different demands and all of them having to do with various Russian institutions not getting services from the private sector," he told reporters. "We have made clear that we're prepared to help on any of these matters."

"Russia is exporting record amounts of grain," O'Brien said. "So if the measurement is food for the globe ... Russia's complaints amount to minor allegations about a system that is working very well."

Russia may export at least 55 million tonnes of grain in the 2023/24 marketing season, slightly less than the estimated record-breaking 57 million tonnes in the 2022/23 season, Russia's Grain Union said last month.

Ukrainian exports for the 2022/23 season were almost 49 million tonnes, according to Agriculture Ministry data. Nearly 33 million tonnes of that was shipped under the Black Sea deal.

Western countries have accused Russia of using food as a weapon of war by quitting the Black Sea deal, which had helped bring down global food prices, and then carrying out repeated air strikes on Ukrainian ports and grain stores.

Russia has complained that not enough Ukrainian grain was getting to the poorest countries. The United Nations has argued that the deal helped everyone because it brought prices down 23% from a record high in the weeks following Russia's invasion. 

https://www.marketscreener.com/quote/currency/US-DOLLAR-RUSSIAN-ROUBL-2370597/news/Russia-says-JPMorgan-stops-processing-its-grain-payments-44527867/

Yankees 1B Rizzo on IL due to post-concussion syndrome from pickoff play collision in May

 New York Yankees first baseman Anthony Rizzo was placed on the injured list on Thursday with post-concussion syndrome, a move that comes more than two months after he sustained a neck injury during a pickoff play.

Rizzo and Yankees manager Aaron Boone said they believed the ailment stems from Rizzo’s collision with Fernando Tatis Jr. of the San Diego Padres in a pickoff attempt on May 28 at Yankee Stadium. Rizzo passed MLB’s concussion testing, but has hit just .172 with one homer in 169 at-bats since the incident. After the game against the Padres, Rizzo was batting .304 with 11 homers in 204 at-bats.

Boone said Rizzo recently told the Yankees’ training staff that he was feeling foggy. He then underwent neurological testing that revealed cognitive impairment.

“Obviously, the struggles have been real documented, and in this game, you try to figure out what is going on whenever you’re struggling,” Rizzo said before the Yankees opened a four-game series against the Houston Astros. “I guess now we can think two and two together, but over the last few weeks, you start going to the different checklists of mechanics, timing, consistently being late. Why am I consistently being late? I’ve made this adjustment plenty of times in my career, I didn’t forget how, to all of a sudden, do this.”

Boone said Rizzo is considered week to week. Rizzo, who will be taking three supplements designed to treat concussions, is allowed to participate in physical activity.

“They said it could be a week, it could be two weeks,” Rizzo said. “They don’t know. But for me, I think it takes all the stress out of wondering now. Now you know there’s a treatment plan. My body usually responds really well to that in the past.”

https://apnews.com/article/rizzo-yankees-injured-concussion-astros-86ebbf86ae36865e728e49d77a720337

Former first-round NBA draft pick is sentenced to 10 years in prison in $4M health care fraud

 A federal judge sentenced a former first-round NBA draft pick to 10 years in prison Thursday, saying he used his people skills to entice others to aid his $5 million health care fraud after he “frittered away” substantial earnings from his professional career.

Terrence Williams, 36, of Seattle, was also ordered to forfeit more than $650,000 and to pay $2.5 million in restitution for ripping off the NBA's Health and Welfare Benefit Plan between 2017 and 2021 with the help of a dentist in California and doctors in California and Washington state. Profits were generated by claims for fictitious medical and dental expenses.

Prosecutors said fraudulent invoices created by the medical professionals were processed by other people whom Williams recruited to defraud the plan, which provides health benefits to eligible active and former NBA players and their families.

“You were yet another player who frittered away substantial earnings from the period of time when you were playing basketball professionally,” Judge Valerie E. Caproni told him. “You should have had enough money to be set for life, but you don't.”

Williams was picked No. 11 in the 2009 draft by what was then the New Jersey Nets. Before his career ended in 2013, he played for the Nets, Boston Celtics, Houston Rockets and Sacramento Kings.

Williams had pleaded guilty to conspiracy to commit health care and wire fraud and aggravated identity theft in a case that resulted in criminal charges against 18 former NBA players. So far, 13 have pleaded guilty to charges. Of those who have been sentenced, many have received “time served” or probation, meaning they didn't have to go to prison. At least 10 of the ex-players paid kickbacks totaling about $230,000 to Williams, authorities said.

For the most part, the ex-players charged had journeyman careers playing for several different teams and never reached anywhere close to the enormous stardom or salary that top players command.

Still, the 18 players made a combined $343 million during their on-court NBA careers, not counting outside income, endorsements or what any may have made playing overseas.

Before the sentence was announced, Williams choked up repeatedly as he blamed his crime on “stupidity and greed” and said he regretted that his incarceration will keep him from his six children, two of whom are now adults.

“I one million percent take full accountability for my role in this case,” he said.

He added that he came to court “humble and humiliated” as he blamed his turn toward crime in part on an opioid addiction that developed after he took painkillers to cope with the pain of lingering injuries from his professional career.

The judge, though, said it appeared that he used his big personality to lure friends and others to join him in a scheme to steal money because he didn't want to seek legitimate employment.

She said his behavior was “extortionate, aggressive." And his motivation, she added, "was greed.”

“You think first and foremost about yourself and not others,” Caproni said.

She said she was going to require him to participate in a program that teaches how to manage money. As for what happened to his NBA earnings, she said: “My guess is it was just frittered away on stupid stuff.”

U.S. Attorney Damian Williams said the defendant who played for Louisville in college recruited medical professionals and others to carry out a criminal conspiracy and maximize illegal profits.

"Williams not only lined his pockets through fraud and deceit, but he also stole the identities of others and threatened a witness to further his criminal endeavors. For his brazen criminal acts, Williams now faces years in prison.”

Williams has been incarcerated since May 2022, when prosecutors alleged that he sent threatening phone texts to a witness in the case.


https://abcnews.go.com/Health/wireStory/former-round-nba-draft-pick-sentenced-10-years-102001058