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Tuesday, April 9, 2024

Positive Results for Intranasal Oxytocin in Adults With Autism

 Twice daily intranasal oxytocin has been associated with improved social functioning, quality of life, and overall symptoms in adults with autism spectrum disorder (ASD), results of a small randomized control trial showed.

"One of the challenges for adults with autism is experiencing poor social interactions and difficulties in making friends. Insufficient social support from peers, friends, and family members can contribute to loneliness in adolescents with ASD, which in turn leads to anxiety, sadness, and social isolation," said study investigator Saba Faraji Niri, MD, assistant professor of psychiatry, Tehran University of Medical Sciences in Iran. 

Recent US data show is relatively common. In addition, previous research suggests intranasal oxytocin significantly increases activity in brain regions that play a role in establishing social interactions.

To evaluate the therapeutic effects and safety of intranasal oxytocin the researchers randomly assigned 39 adult patients with ASD to receive intranasal oxytocin or placebo with 24 units administered every 12 hours for 8 weeks. 

Faraji Niri said study participants were required to stop all psychotropic medications for at least 8 weeks prior to study entry. 

Participants were assessed at baseline and weeks 4 and 8 using the Autism Quotient, Ritvo Autism Asperger Diagnostic Scale — Revised (RAADS-R), Social Responsiveness Scale (SRS), Clinical Global Impression (CGI) scale, and the World Health Organization Quality of Life-BREF (WHOQL-BREF) questionnaire. Adverse events were also evaluated.

Faraji Niri said that those receiving intranasal oxytocin showed clinical improvement on RAADS-R scores (P = .010), as well as on the social communication subscale of the SRS (P = .002), the CGI scale (P = .000), and the physical (P = .004), psychological (P = .006), and social relationships (P = .046) domains of the WHOQL-BREF. 

However, although the findings were positive, she said at this point it's not possible to draw any definitive conclusions. She noted the study had several potential confounders. These included differences in baseline levels of endogenous oxytocin among study participants individuals, as well as difference in required treatment doses, which were adjusted by age and sex. The presence of comorbidities and interactions with other treatments could also affect the results.

Commenting on the findings for Medscape Medical News, session chair Szabolcs Kéri, PhD, Professor, Sztárai Institute, University of Tokaj, Sárospatak, Hungary, said the use of oxytocin for ASD is controversial. He said that while the research contributes to the scientific debate, the clinical significance of the findings is unclear. 

The investigators and Dr Keri reported no relevant financial disclosures. 

https://www.medscape.com/viewarticle/positive-results-intranasal-oxytocin-adults-autism-2024a10006pj

Jordan Believes Hamas Behind Huge Gaza Protests Which Seek To Sever Ties With Israel

 Via Middle East Eye

Jordanian authorities have clamped down on participants in the daily protests against the Israeli war on Gaza, amid accusations that Hamas has a role in igniting them. Thousands have been protesting daily in Ramadan in front of the Israeli embassy in the capital, Amman, demanding its closure and an end to normalization with Israel in response to its atrocities in Gaza.

The protests continued even though the embassy has no diplomatic mission, following the departure of Israel's ambassador in October and Jordan's recalling of its ambassador in protest of the Israeli war on Gaza. Jordanian authorities have been caught off guard by the size of the Ramadan protests, which average between 6,000 to 10,000 participants

Columnists and former officials have attacked Hamas leaders, especially Khaled Meshaal, accusing the movement and the Muslim Brotherhood of trying to create chaos in Jordan.  Former information minister Samih al-Maaytah accused the Hamas movement abroad of collaborating with the Muslim Brotherhood in Jordan to advance Hamas's political agendas. 

"Hamas abroad is trying to pressure Jordan to restore relations with the movement," he said, citing a speech on March 26 in Amman by Meshaal, the head of Hamas abroad, calling on millions to take to the streets.

"Hamas wants to send a message that it can influence and lead the Jordanian street, which is also convenient for the Iranians who have not been able to exercise any political influence in Jordan," Maaytah told MEE.

Jordanian government spokesperson Muhannad Moubaydeen said on Tuesday that the government did not mind the demonstrations, but was concerned about the chants, which it views as pro-Hamas.

"Jordanian security is charged with protecting the demonstrators and ensuring their safety, but the problem is those who harm national security and come out with unacceptable chants," he said in a press conference. The Muslim Brotherhood in Jordan has rejected these accusations. 

According to Murad al-Adayleh, the Secretary-General of the Islamic Action Front, a party affiliated with the Muslim Brotherhood, "there are no special party interests in these protests, which represent all sectors of Jordanian society that support the Palestinian resistance".

"The Jordanian people's relationship with the Palestinian issue is different from any Arab people because it is geographically and demographically related to Palestine," Adayleh told MEE. "We paid sacrifices and sacrifices from our children for the sake of Palestine, so it is natural for us to see these sit-ins in all cities."

Adayleh said the accusations of Hamas's role in the protests seek to discredit the protest movement, which has so far been the largest in the Arab world. "There are attempts to demonize the Jordanian movement because it has begun to influence the Arab street and has galvanized protests in other Arab countries," he said. 

Jordan was the second Arab country after Egypt to normalise relations with Israel in 1994, in a peace treaty that remains deeply unpopular in the country. Jordanians have also denounced the kingdom's import of Israeli gas as "treasonous".

Hundreds detained

Jordanian security services have detained hundreds of political activists from different parties since the beginning of the 7 October war. Lawyer and former judge Louay Obeidat said that more than 1,500 activists have been prosecuted for their protest activities

Many of them have been released, but dozens remain in administrative detention, while seven are considered to have been forcibly disappeared. Among the detainees was trade union activist Maysara Malas, who has been in administrative detention, held without charge for the past four months in connection with the protests.

Malas's family said that 20 members of the General Intelligence raided his house in al-Rashid suburb at dawn on 4 January to arrest him. During the raid, the officers asked all family members to turn off their phones, searched the house and Malas's car, and confiscated documents, electronic devices and surveillance camera tapes, the family said in a statement. 

After an hour-and-a-half-long search of their house, Malas was handcuffed and detained without any charge. He remains in detention at the General Intelligence Department, and his lawyer has been prevented from visiting him, according to the family. 

The National Alliance for Rights and Freedoms, a group of human rights activists, said that the Jordanian authorities pursued a huge number of activists in connection with the sit-in near the Israeli embassy.

https://www.zerohedge.com/geopolitical/jordan-believes-hamas-behind-huge-gaza-protests-which-seek-sever-ties-israel

How Trump Could Beat Deep State

Let’s say that Trump wins the November election. What would a second Trump presidency actually look like?

Today we’re going to investigate that question. Let’s first back up to the 2016 election.

Trump ran the most incompetent presidential transition process in my lifetime and perhaps the worst in history. The problems began with the fact that none of Trump, his family members and inner circle actually thought he would win the 2016 election with the exception of campaign manager Steve Bannon.

I predicted Trump would win but I was almost alone in that regard.

Trump picked Chris Christie as his transition manager, seemingly oblivious to the fact that as a prosecutor, Christie had put Jared Kushner’s father in jail. Given Kushner’s role as Trump’s son-in-law and close adviser, this was a recipe for failure.

A well-run transition doesn’t start the day after the election. It begins a year or more advance with a list of loyal appointees ready to go. Trump had no preparation and no team. Christie was fired as transition manager and Mike Pence took over, but the entire process was bungled.

The other problem was that Trump applied the New York real estate developer mentality to his administration. He never worried much about his appointees because if they failed, he could always yell, “You’re fired!”

That may work in New York, but it doesn’t work in Washington. Appointees are protected by politicians, lobbyists and the media. If you fire someone, you can expect a barrage of leaks, policy paralysis and opposition to any new appointee.

Even if a bad choice is fired, the lower levels of the deep state take over and run rings around you while waiting for a replacement who will take months to get a handle on the job in a best case.

Trump never understood any of this.

Trump also trusted the wrong people. He installed James Mattis as secretary of defense, Rex Tillerson as secretary of state, H.R. McMaster as national security adviser and John Kelly as chief of staff. They were all RINOs from the Bush wing of the party.

They were brought in as “adult supervision” of the supposedly reckless Trump, but they all stabbed Trump in the back. Meanwhile, loyal supporters like Steve Bannon and K.T. McFarland were shoved aside.

Trump didn’t learn. He did fire James Comey as head of the FBI (three months too late) but then appointed Christopher Wray as the new FBI director. Wray now works for Biden and puts Trump supporters in jail. But Trump was the one who appointed him.

Trump should have fired the lying Anthony Fauci after one meeting. Instead, he gave Fauci the keys to the U.S. economy. Fauci then implemented lockdowns, school closings, vaccine mandates, masking and social distancing in ways that ruined the U.S. economy and gave Trump’s enemies an excuse to change election laws to favor mail-in ballots, which permits more widespread cheating.

The list goes on. The bottom line is no one was worse at transition planning, appointments, endorsements and tolerance of gross incompetence than Trump. He was his own worst enemy and seemed incapable of learning the ropes in how to deal with Washington bureaucracy and the deep state.

This leaves one overriding question. Has Trump learned anything since leaving office in 2021? Will he have a successful transition this time or simply repeat the blunders of 2017–2021?

Read on to see how Trump could pull it off.


How to Take on the Deep State

Has Trump learned anything since leaving office in 2021? Will he have a successful transition this time or simply repeat the blunders of 2017–2021? To answer those questions, we turn to two books that hold the key to possible success in a new Trump administration. The first is called The Plum Book. The second is called Mandate for Leadership 2025.

“Plum Book” is a nickname for a publication from the Government Printing Office based on the fact that it has a plum-colored cover. The official title is United States Government Policy and Supporting Positions.

It’s a 232-page directory of about 8,000 jobs in the U.S. government with an emphasis on the executive branch (controlled by the president) and independent agencies such as the Federal Communications Commission (FCC), the National Endowment for the Arts (NEA) and the Securities and Exchange Commission (SEC). It’s literally page after page of job listings by title, department and pay grade.

What makes the Plum Book special (and indispensable to a presidential transition team) is that the jobs listed in the book are those that are open to political appointment and not subject to a competitive process.

These are the jobs where the president can just pick the person he wants and install that person in a key policy position without going through normal civil service channels. Some of the positions may be subject to Senate confirmation, but that usually poses no difficulty, especially if the new president’s party also controls the Senate.

The Plum Book is like a secret guide to understanding the deep state and putting your own people in place to control it.

Even the most obscure federal agencies have top positions to be filled. They all have a director, one or more deputies, board members, executive assistants, etc. That’s how deep the deep state really is. When Biden calls for an “all of government” approach to climate change or DEI, the Plum Book tells us that means 8,000 hands on deck.

The executive office of the president involves a lot more than 10 or so close assistants in the West Wing such as counsel to the president, chief of staff and a few special assistants. The Plum Book lists 83 separate jobs (not including clerks, interns and executive assistants).

These jobs support the president only and do not come close to covering the entire executive branch. Among these positions are “special assistant to the president and assistant communications director for strategic messaging,” and “special assistant to the president and deputy director of White House information technology.” As you can see, even the assistants and deputies have assistants and deputies.

So if Trump wins the election, the Plum Book will be an important tool to put the right people in place..

Still, the Plum Book is only the beginning of a successful transition. It tells us what positions need to be filled but does not offer a guide to policy. The selection of individuals for appointments needs to be guided by a set of policies that can act as a filter for choosing the right individuals.

Who is doing the hard work of outlining policy initiatives for hundreds of agencies, commissions and offices that comprise the executive branch and ultimately the deep state? It’s fine to win an election and use the Plum Book to fill key positions with competent loyalists, but what policies will they actually implement?

Fortunately for Trump, the Heritage Foundation has done this work. The Heritage Foundation is just one of hundreds of think tanks and policy centers in Washington, D.C. But in 2024 they’ve taken the lead in collecting and publishing policy papers on hundreds of key issues.

Their work is called Mandate for Leadership 2025. I call it the Trump playbook. It’s available online at the Heritage Foundation website. It’s 887-pages long and every page is filled with technical discussion.

The content is conservative but not ideological. There is a fair balance and even competing perspectives. In the section on trade, there is “The Case for Fair Trade” by Peter Navarro and “The Case for Free Trade” by Kent Lassman. It’s likely that the best policy includes some content from both perspectives depending on the specific trading partner, reciprocity and the impact on U.S. jobs.

The Heritage Foundation playbook Mandate for Leadership, combined with the Plum Book and Trump’s apparent willingness to learn from his past mistakes when it comes to appointments completes the Trifecta needed for success in a second Trump administration to destroy the deep state. Investors should hope that Trump stays on that path and listens to the hundreds of experts and institutions that are working hard to make that success a reality.

The difference for investors between another Biden administration and the return of Trump to the White House could not be more stark. The Biden administration has been characterized by excessive regulation, pointless mandates as part of the Green New Scam, open borders bringing crime, drugs and cartel influence into the United States, disastrous wars in Ukraine, Gaza and now the closing of the Red Sea-Suez Canal passage, increased segregation of Blacks in colleges, the destruction of 50 years of progress in women’s sports by allowing competition by men and a long list of other ruinous policies.

The first Trump administration was characterized by business and personal tax cuts, reduced regulation, no new wars, outreach to nuclear rivals such as Russia and North Korea, tariffs on unfair trade by China, a concerted effort to bring manufacturing jobs back to the United States, demands that NATO members pay their fair share for mutual defense and a secure southern border with Mexico.

Trump also made an historic three appointments to the Supreme Court, which has emerged as practically the last bastion of constitutional order and the rule of law. There’s no reason to expect any improvement in another Biden administration. In fact, policies will almost certainly grow worse as Biden fails physically and mentally and opens the door to a possible acting president in the form of Kamala Harris, a known dunce.

There’s good reason to believe that a second Trump administration will offer the growth-oriented policies of the first administration with a much more effective decision-making apparatus resulting from attention to the Plum Book, the playbook and the transition process.

A better transition process in a second term means the biggest threat to the deep state in decades. And a new team will put us on the road back to sanity. But powerful people won’t go quietly. A more experienced Trump will conduct a second war to destroy them. Unless they destroy him first.

https://dailyreckoning.com/how-trump-could-beat-deep-state/

Japan Firms Warn AI Could Cause Total Collapse Of Social Order

 by Paul Joseph Watson via Modernity.news,

Two top Japanese companies have warned that artificial intelligence could cause a total collapse of the social order if it is not rapidly reigned in.

Nippon Telegraph and Telephone (NTT) and Yomiuri Shimbun Group Holdings, the country’s largest telecommunications company and the country’s biggest newspaper, jointly published the AI manifesto.

It warned that if legislation is not passed quickly in major countries across the world, artificial intelligence threatens to decimate democracy and provoke widespread societal unrest.

Pointing to AI programs being developed by US tech giants, the manifesto warns, “In the worst-case scenario, democracy and social order could collapse, resulting in wars.”

The report stated that such technology is designed to seize users’ attention with little regard for morality or accuracy.

Guided by Keio University researchers, the companies called on the Japanese government to pass new laws to protect elections and national security from AI.

As we previously highlighted, programs such as Google’s Gemini AI system caused fury after they openly discriminated against white people and in some cases erased them from history altogether.

OpenAI’s ChatGPT produced equally ludicrous content, in one case saying it would refuse to quietly utter a racial slur that no human could hear in order to save 1 billion white people from a “painful death.”

*  *  *

https://www.zerohedge.com/geopolitical/japan-warns-ai-could-cause-total-collapse-social-order

'Bird Flu-Pocalypse' Forces Hong Kong To Suspend Some Imports Of US Poultry Meat

 The recent spread of bird flu—also known as highly pathogenic avian influenza, or HPAI— across several US states has been hyped by corporate media. Some journalists are quoting 'experts' who warn the bird flu pandemic could be '100 times worse' than Covid.' 

According to Bloomberg data, the story count in corporate media for all things "Bird Flu" last week hit a record high on data going back to 2014.

The context here is crucial. Bird flu is not just a US issue anymore; it's 'going global,' and this is happening just before the US presidential elections in November.  

On Tuesday, Hong Kong's food safety authority published a memo stating, "Import of poultry meat and poultry products suspended in some areas of the United States." 

Here's the full memo from the Center for Food Safety (CFS) of the Food and Environmental Hygiene Department:

The Center for Food Safety (CFS) of the Food and Environmental Hygiene Department announced today (April 9) that in response to a notification from the World Organization for Animal Health regarding an outbreak of highly pathogenic H5N1 avian influenza in Ionia County, Michigan, and Parmer County, Texas, USA, The CFS immediately instructed the trade to suspend the import of poultry meat and poultry products (including poultry eggs) from the above-mentioned areas to protect public health in Hong Kong.

A spokesman for the CFS said that according to the Census and Statistics Department, Hong Kong imported about 37,770 tonnes of chilled and frozen poultry meat and about 83.84 million poultry eggs from the United States last year.

The spokesman said: "The CFS has contacted the US authorities regarding the incident and will continue to closely monitor information on the outbreak of avian influenza from the World Organization for Animal Health and relevant authorities, and will take appropriate actions in light of the development of the local epidemic."

If it's bird flu or whatever "Disease X" could possibly be, there appears to be a push to "intersect" some type of 'Covid crisis' before the 2024 US elections.

"They will surely try to run their "Disease X" ruse. But they have already lost the trust of the people they made war against in their own country. In which case, expect resistance among the un-sick," James Howard Kunstler penned in a note earlier this month.

https://www.zerohedge.com/commodities/bird-flu-pocalypse-forces-hong-kong-suspend-some-us-poultry-meat

15 US Agencies Knew Wuhan Lab Was "Trying To Create A Coronavirus Like COVID-19": Rand Paul

 While a massive body of evidence exists on the origins of COVID-19, Senator Rand Paul (R-KY) is conducting his own investigation into the matter.

In a Tuesday op-ed, Paul writes that government officials from 15 federal agencies "knew in 2018 that the Wuhan Institute of Virology was trying to create a coronavirus like COVID-19."

These officials knew that the Chinese lab was proposing to create a COVID 19-like virus and not one of these officials revealed this scheme to the public. In fact, 15 agencies with knowledge of this project have continuously refused to release any information concerning this alarming and dangerous research.

Government officials representing at least 15 federal agencies were briefed on a project proposed by Peter Daszak’s EcoHealth Alliance and the Wuhan Institute of Virology. -Rand Paul

Paul is talking about the DEFUSE project, which was revealed after DRASTIC Research uncovered documents showing that DARPA had been presented with a proposal for EcoHealth to perform gain-of-function research on bat coronavirus.

And according to Rand Paul, officials from 15 agencies knew about this. While the project was never funded (DARPA called it too dangerous) - Paul writes: "This project, the DEFUSE project, proposed to insert a furin cleavage site into a coronavirus to create a novel chimeric virus that would have been shockingly similar to the COVID-19 virus."

And what does this mean?

It means that at least 15 federal agencies knew from the beginning of the pandemic that EcoHealth Alliance and the Wuhan Institute of Virology were seeking federal funding in 2018 to create a virus genetically very similar if not identical to COVID-19.

Disturbingly, not one of these 15 agencies spoke up to warn us that the Wuhan Institute of Virology had been pitching this research. Not one of these agencies warned anyone that this Chinese lab had already put together plans to create such a virus.

Peter Daszak concealed this proposal. University of North Carolina scientist Ralph Baric, a named collaborator on the DEFUSE project, failed to reveal that the Wuhan Institute of Virology had already proposed to create a virus similar to COVID-19.

And now we know that 15 agencies heard the proposal and when each agency discovered that COVID-19 was strangely similar to DEFUSE’s proposed virus creation, not one agency head stepped forward to warn the public that the virus might be man-made and therefore already adapted to transmit freely among humans. -Rand Paul

Paul further writes that Fauci's NIAID was not only briefed on the DEFUSE proposal, his "Rocky Mountain Lab" was named as a partner in it along with the Wuhan Institute of Virology.

Meanwhile, researcher Ian Lipkin, one of the authors of the "proximal origins" coverup paper, was also part of the DEFUSE plan - which he never revealed publicly.

"Did NIAID warn us? Did Anthony Fauci warn us? No! All lips remained sealed," writes Paul.

https://www.zerohedge.com/covid-19/15-us-agencies-knew-wuhan-lab-was-trying-create-coronavirus-covid-19-rand-paul

Moscow Accuses Hunter Biden-Linked Company Burisma Of Financing Terror Attacks

 Russia says it has uncovered more damning evidence connecting the US and NATO to recent terror and assassination campaigns in Russia, including making connections to the March 22 Crocus City Hall terror attack which resulted in over 140 Russians dead and hundreds more wounded and injured.

Russia's Investigative Committee, which is the country's top investigative body, announced Tuesday that it has launched a criminal probe into senior US and Western officials who are believed to be "financing terrorism"

The formal statement claims that an ongoing investigation has "established" that money from commercial organizations tied to NATO were used to "eliminate prominent political and public figures" inside and outside Russia, as well as to "inflict economic damage" against the country. Lately there's also been a spate of devastating cross-border attacks on refineries, ports, and oil facilities.

Another major event and probe which is high on the Kremlin's agenda is the August 20, 2022 assassination of Darya Dugina outside of Moscow, in a car bombing which authorities believe was likely intended to kill her father, Alexander Dugin, prominent philosopher and pundit who is seen as a close ally of President Putin. There's also the assassination of famous pro-Kremlin military blogger Vladlen Tatarsky, killed in an April 2023 cafe bombing in St. Petersburg..

While it is nothing new that Russian officials would raise suspicions that such targeted attacks had covert NATO support, whether directly or indirectly, what is new - and a bit surprising - is that the name Burisma Holdings appears in the fresh statement of the Russian Investigative Committee. 

This name is of course very familiar and notorious in the West, as AFP and Moscow Times report Tuesday:

The top law enforcement body named the Ukrainian energy company Burisma Holdings as one of the implicated organizations. U.S. President Joe Biden’s son Hunter Biden served as a member of Burisma’s board of directors between 2014 and 2019.

His role has fueled Republican accusations against the Biden family over claimed corruption and culminated in an ongoing impeachment probe in U.S. Congress. Hunter Biden has denied any wrongdoing, and a former FBI informant was arrested in February on suspicion of fabricating accusations against the president’s family.

The Russian investigative body described that it is still examining "sources and movement of several million U.S. dollars and the involvement of specific persons from government officials and public commercial organizations of Western countries."

It said further it is seeking to expose "links of the direct perpetrators of terrorist acts with their foreign curators, organizations and sponsors" — however without naming specific countries or specific terror attack or assassinations (other than identifying Burisma).

Just like with US media over the past several years, Burisma has been featured prominently in Russian state media reporting. Below is the precise section from Tuesday's official statement naming Burisma (according to machine translation):

It has been established that funds received through commercial organizations, in particular, the oil and gas company Burisma Holdings, operating in Ukraine, have been used in recent years to carry out terrorist acts in the Russian Federation, as well as beyond its borders in order to eliminate prominent political and public figures and causing economic damage. —Russian Investigative Committee

This marks a first over the course of the more than two year long Russia-Ukraine war. Recently, Ukraine has stepped up its cross-border drone and missile attack on Russian soil. Moscow has all along complained that these attacks are sophisticated and long-range enough (with long-range attacks especially wreaking havoc on Russian oil facilities) that they must have CIA or Western intelligence help. 

Conservative media was abuzz Tuesday after a familiar name resurfaced, this time over alleged links to terror financing...

It appears that the Kremlin is now not just pointing the finger at Western governments, but at commercial entities within Ukraine which have long established Western business ties. It seems the theory is that companies like Burisma are continuing to play a 'middle man' role in term of 'terror financing' for attacks on Russian soil.

Washington has repeatedly rejected Russian allegations that the US is involved in these attacks. Yet as we've recently detailed, more and more US mainstream media reporting has of late been offering surprising clarity on the CIA's role in assisting Ukraine with mounting high-risk cross border attacks on Russian soil of late.

https://www.zerohedge.com/geopolitical/moscow-accuses-hunter-biden-linked-company-burisma-financing-terror-attacks