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Monday, June 10, 2024

Anti-Israel mob chants ‘Long Live Intifada’, lights flares at NYC memorial to Oct. 7 music fest victims

 A mob of anti-Israel protesters chanted “Long Live the Intifada” during a depraved celebration Monday night outside a downtown Manhattan exhibit that memorializes the murder and rape victims of the Oct. 7 Nova Music Festival where 364 people were killed by Hamas terrorists.

The deranged pro-terror crowd lit flares and waved a flag associated with the Iran-backed Lebanese terrorist group Hezbollah in front of the Nova Music Festival Exhibition on Wall Street during what was billed by organizers as a “citywide day of rage for Gaza,” according to video from the scene.

The mob of anti-Israel protesters lit flares and chanted “Long Live the Intifada” outside a downtown Manhattan exhibit.FNTV
The group lit red and green flares.FreedomNewsTV

The protesters also yelled “Israel go to hell” and clashed with police during the disturbing gathering that drew swift backlash from Israel supporters. 

“How utterly evil do you have to be to protest outside a site that memorializes the 1,200 victims of October 7?” former speechwriter for the Israeli government Aviva Klompas tweeted.

“Tonight’s viscous targeting of the exhibition is not pro-peace. It is repulsive and vile. I condemn it in the strongest possible terms,” added Manhattan Borough President Mark Levine in a post on X. “I condemn it in the strongest possible terms.” 

New York GOP Rep. Michael Lawler also called the actions of protesters “disgusting.”

The crowd of demonstrators clashed with police.FreedomNewsTV

“There’s only one reason why these protesters would march in front of a Manhattan exhibit in memory of those killed at the Nova music festival on October 7th,” Joel Petlin, superintendent of the Kiryas Joel School District, said in a social media post.

“They support the terrorists who perpetrated it, and they want it to happen again.”

Anti-Defamation League CEO Jonathan Greenblatt previously said in April a call for intifada is to “call for violence against Israelis and Jews and Israel.”

Protesters marching and rallying on Wall Street.FreedomNewsTV

The Nova Exhibit was unveiled in April to give New Yorkers an idea of the terror that Hamas inflicted on Israel on Oct. 7, including when the “Tribe of Nova” festival in southern Israel was attacked. 

“The installation sets out to recreate an event dedicated to peace and love that was brutally cut short by Hamas’s attack on Israel from Gaza on that fateful day,” according to its website.

The exhibit is expected to last through the end of this week.

The exhibit memorializes the victims of the Oct. 7 Nova Music Festival massacre.X / @martinlieberman

On top of the hundreds of concert-goers killed at the festival, a United Nations envoy said in March there are “reasonable grounds” that Hamas terrorists committed rape and “sexualized torture” during the horrifying assault in southern Israel.

The demonstration, organized by pro-Palestinian group Within Our Lifetime, began in Union Square where some protesters unfurled a banner that stated “Long live October 7th,” according to social media footage.

A few blocks from the exhibit at Zuccotti Park, one man who was purportedly an Israel supporter was surrounded and taunted by about a dozen protesters who called him a Zionist.

At another point, police and protesters also faced off when officers demanded protesters get outside the barriers lining the street.

The protests against Israel have been ongoing since the Jewish state was attacked by Hamas terrorists last year.X / @UJAfedNY

Several smoke bombs were set off and a yellow-and-green flag of the Iran-backed terror group Hezbollah was raised during the protest, according to video.

The protests against Israel have been ongoing since the Jewish state was attacked by Hamas terrorists last year, leading to the slaughter of 1,200 people and an ensuing military campaign in Gaza by the Israeli military.

Protesters shouted “shame” at Memorial Sloan Kettering Cancer Center on the Upper East Side earlier this year and also berated Alec Baldwin last year as he walked by a demonstration.

Anti-Israel agitators have also blocked city roadways and occupied transit hubs during the months of protesting.

https://nypost.com/2024/06/10/us-news/anti-israel-mob-chanting-long-live-intifada-light-flares-outside-nyc-exhibit-that-memorializes-oct-7-nova-music-festival-victims/

'Testing immune cells in placenta may indicate health of fetal brain immune cells'

 Immune activation in a pregnant woman can have negative effects on the development of fetal brain microglia—or macrophage immune cells in the brain—and even lead to neurodevelopmental disorders in newborns.

It's not possible to monitor how  are developing within the , but new research indicates that the health of fetal macrophages in the placenta can act as an indicator of the health of fetal brain microglia.

The research was led by investigators from Massachusetts General Hospital and is published in Cell Reports.

"If we can use fetal placental macrophages as a surrogate cell type or biomarker for fetal brain microglial programming, we have the opportunity to identify those children at greatest risk from in utero immune-activating exposures. Identifying these children early creates the potential to intervene during key developmental windows to ameliorate the impact of those pregnancy exposures," said senior author Andrea Edlow, MD MSc, an associate professor of Obstetrics, Gynecology, and Reproductive Biology, and a Maternal-Fetal Medicine specialist at Massachusetts General Hospital. Dr. Edlow is also an MGH Research Scholar.

Examples of immune-activating exposures during pregnancy include bacterial and , metabolic inflammation from obesity and diabetes, environmental toxins and maternal stress. Edlow and her colleagues assessed placental macrophages in a mouse model of maternal diet-induced obesity.

Single-cell RNA sequencing of mouse fetal placental macrophages (or Hofbauer cells) revealed similar gene expression signatures as fetal brain microglia during normal conditions and also in response to maternal diet-induced obesity.

Interestingly, the sex of the fetus impacted how maternal obesity affects the placenta and the fetal brain. Specifically, male placental macrophages and fetal brain microglia had a greater number of genes dysregulated by maternal obesity and more neuroinflammatory signaling than female cells.

When the investigators compared their mouse data with published human datasets, they found conserved gene expression patterns in placental macrophages in mice and humans, suggesting that their findings in mice may have clinical implications in humans.

"This work is a promising start for using fetal placental macrophages as a biomarker for fetal brain microglial programming in a variety of maternal exposures, and it could form the basis for creating personalized fetal models of neurodevelopment using cells from the placenta that are easily accessible at birth," said Edlow.

More information: Rebecca Batorsky et al, Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity, Cell Reports (2024). DOI: 10.1016/j.celrep.2024.114326


https://medicalxpress.com/news/2024-06-immune-cells-placenta-health-fetal.html

'Skin-inspired sensory robots to provide medical treatment'

University of North Carolina at Chapel Hill scientists have created innovative soft robots equipped with electronic skins and artificial muscles, allowing them to sense their surroundings and adapt their movements in real-time, according to a paper titled "Skin-Inspired, Sensory Robots for Electronic Implants," in Nature Communications.

In their research, the robots are designed to mimic the way muscles and skin work together in animals, making them more effective and safer to use inside the body. The e-skin integrates various sensing materials, such as silver nanowires and  within a flexible base, closely resembling the complex sensory functions of real skin.

"These  can perform a variety of well-controlled movements, including bending, expanding and twisting inside biological environments," said Lin Zhang, first author of the paper and a postdoctoral fellow in Carolina's Department of Applied Physical Sciences. "They are designed to attach to tissues gently, reducing stress and potential damage. Inspired by natural shapes like starfish and seedpods, they can transform their structures to perform different tasks efficiently."

These features make soft sensory robots highly adaptable and useful for enhancing medical diagnostics and treatments. They can change shape to fit organs for better sensing and ; are capable of continuous monitoring of internal conditions, like bladder volume and blood pressure; provide treatments, such as , based on  data; and can be swallowed to monitor and treat conditions in the stomach.

An ingestible robot capable of residing in the stomach called a thera-gripper, can monitor pH levels and deliver drugs over an extended period, improving treatment outcomes for gastrointestinal conditions. The thera-gripper can also gently attach to a beating heart, continuously monitoring electrophysiological activity, measuring cardiac contraction and providing electrical stimulation to regulate heart rhythm.

A robotic gripper designed to wrap around a person's bladder can measure its volume and provide electrical stimulation to treat the overactive one, enhancing patient care and treatment efficacy. A robotic cuff that twists around a blood vessel can accurately measure  in real time, offering a non-invasive and precise monitoring solution.

"Tests on mice have demonstrated the thera-gripper's capability to perform these functions effectively, showcasing its potential as a next-generation cardiac implant," said Zhang.

The Bai Lab collaborated on the study with UNC-Chapel Hill researchers in the Department of Biology; Department of Biomedical Engineering; Department of Chemistry; Joint Department of Biomedical Engineering and McAllister Heart Institute; North Carolina State University; and Weldon School of Biomedical Engineering at Purdue University.

The researchers' success in live animal models suggests a promising future for these robots in real-world medical applications, potentially revolutionizing the treatment of chronic diseases and improving patient outcomes.

"This innovative approach to robot design not only broadens the scope of medical devices but also highlights the potential for future advancements in the synergistic interaction between soft implantable robots and biological tissues," said Wubin Bai, principal investigator of the research and Carolina assistant professor. "We're aiming for long-term biocompatibility and stability in dynamic physiological environments."

More information: Lin Zhang et al, Skin-inspired, sensory robots for electronic implants, Nature Communications (2024). DOI: 10.1038/s41467-024-48903-z


https://medicalxpress.com/news/2024-06-skin-sensory-robots-medical-treatment.html

'First-in-kind protocol for creating 'wired miniature brains''

 Researchers worldwide can now create highly realistic brain cortical organoids—essentially miniature artificial brains with functioning neural networks—thanks to a proprietary protocol released this month by researchers at the University of California San Diego.

The new technique, published in Nature Protocols, paves the way for scientists to perform more advanced research regarding autism, schizophrenia and other neurological disorders in which the brain's structure is usually typical, but electrical activity is altered.

That's according to Alysson Muotri, Ph.D., corresponding author and director of the UC San Diego Sanford Stem Cell Institute (SSCI) Integrated Space Stem Cell Orbital Research Center. The SSCI is directed by Dr. Catriona Jamieson, a leading physician-scientist in cancer stem cell biology whose research explores the fundamental question of how space alters cancer progression.

The newly detailed method allows for the creation of tiny replicas of the human brain so realistic that they rival "the complexity of the fetal brain's neural network," according to Muotri, who is also a professor in the UC San Diego School of Medicine's Departments of Pediatrics and Cellular and Molecular Medicine. His brain replicas have already traveled to the International Space Station (ISS), where their activity was studied under conditions of microgravity.

Two other protocols for creating brain organoids are publicly accessible, but neither allow researchers to study the brain's . Muotri's method, however, allows researchers to study  created from the stem cells of patients with various neurodevelopmental conditions.

"You no longer need to create different regions and assemble them together," said Muotri, adding that his protocol allows different brain areas—like the cortex and midbrain—"to co-develop, as naturally observed in human development."

"I believe we will see many derivations of this protocol in the future for the study of different brain circuits," he added.

UC San Diego develops first-in-kind protocol for creating 'wired miniature brains'
Brain cortical organoids are examined under an electronic microscope. Muotri recently published his method for making such organoids, which he says are so realistic that they "rival the complexity of the fetal brain's neural network." Credit: UC San Diego Health Sciences

Such "mini-brains" can be used to test potentially therapeutic drugs and even gene therapies before patient use, as well as to screen for efficacy and side effects, according to Muotri.

A plan to do so is already in the works. Muotri and researchers at the Federal University of Amazonas in Manaus, Amazonas, Brazil, are teaming up to record and investigate Amazonian tribal remedies for Alzheimer's disease—not on Earth-based mouse models, but on diseased human brain organoids in space.

The research project spans multiple continents and habitats, from the depths of the Amazon rainforest to Muotri's lab on the coast of California—and, eventually, will reach the International Space Station.

Other research possibilities for the brain organoids include disease modeling, understanding human consciousness and additional space-based experiments. In March, Muotri—in partnership with NASA—sent to space a number of  organoids made from the stem cells of patients with Alzheimer's disease and ALS (, also known as Lou Gehrig's disease). The payload returned in May and the results, which will eventually be published, are being reviewed.

Because microgravity mimics an accelerated version of Earth-based aging, Muotri should be able to witness the effects of several years of disease progression while studying the month-long mission's payload, including potential changes in protein production, signaling pathways, oxidative stress and epigenetics.

"We're hoping for novel findings—things researchers haven't discovered before," he said. "Nobody has sent such a model into space, until now."

Co-authors of the study include Michael Q. Fitzgerald, Tiffany Chu, Francesca Puppo, Rebeca Blanch and Shankar Subramaniam, all of UC San Diego, and Miguel Chillón, of the Universitat Autònoma de Barcelona and the Institució Catalana de Recerca i Estudis Avançats, both in Barcelona, Spain. Blanch is also affiliated with the Universitat Autònoma de Barcelona.

More information: Michael Q. Fitzgerald et al, Generation of 'semi-guided' cortical organoids with complex neural oscillations, Nature Protocols (2024). DOI: 10.1038/s41596-024-00994-0


https://medicalxpress.com/news/2024-06-team-kind-protocol-wired-miniature.html

'Study shows first evidence of sex differences in how pain can be produced'

 Research suggests that males and females differ in their experience of pain, but up until now, no one knew why. In a recent study published in Brain, University of Arizona Health Sciences researchers became the first to identify functional sex differences in nociceptors, the specialized nerve cells that produce pain.

The findings support the implementation of a precision medicine-based approach that considers patient sex as fundamental to the choice of treatment for managing pain.

"Conceptually, this paper is a big advance in our understanding of how pain may be produced in males and females," said Frank Porreca, Ph.D., research director of the Comprehensive Center for Pain & Addiction at UArizona Health Sciences and professor and associate department head of pharmacology at the UArizona College of Medicine-Tucson. "The outcomes of our study were strikingly consistent and support the remarkable conclusion that nociceptors, the fundamental building blocks of pain, are different in males and females. This provides an opportunity to treat pain specifically and potentially better in men or women, and that's what we're trying to do."

Porreca and the research team focused their study on the excitability of nociceptor cells located near the  in the dorsal root ganglion. Nociceptors, when activated by damage or injury, send a signal through the spinal cord to the brain that results in the perception of pain. Nociceptors are also adaptable in their response to injury.

For example, touching a hot stove is a high-intensity stimulus, while a shirt collar rubbing a sunburn is low-intensity, yet both produce the perception of pain. In injury settings such as sunburn, pain medications, including nonsteroidal anti-inflammatory drugs such as ibuprofen, work by normalizing the threshold for nociceptor activation, thereby blocking pain produced by low-intensity stimuli such as the rubbing of a shirt.

Following up on prior research on the relationship between  and sleep, unexpected sex differences led Porreca to choose two substances—prolactin and  B—for this study. Prolactin is a hormone responsible for lactation and breast tissue development; orexin is a neurotransmitter that helps to promote staying awake. However, both prolactin and orexin have many other functions that are only now being revealed.

The research team used  from male and female mice,  and humans to test the effect of prolactin and orexin B on nociceptor activation thresholds that can allow low-intensity stimuli to produce pain.

"What we found is that in males and females—animals or humans—what changes the thresholds of the nociceptors can be completely different," Porreca said. "When we added the sensitizing substances that lower these thresholds for activation, we found that prolactin only sensitizes female cells and not male cells, and orexin B only sensitizes male cells and not female cells. The startling conclusion from these studies is that there are male nociceptors and female nociceptors, something that has never previously been recognized."

Taking the research one step further, they then blocked prolactin signaling and orexin B signaling and examined the effect on the threshold for activation of the nociceptors. As anticipated, blocking prolactin signaling reduced nociceptor activation in females and had no effect in males, while blocking orexin B signaling was effective in males and not in females.

"Until now, the assumption has been that the driving mechanisms that produce pain are the same in men and women," Porreca said. "What we found is that the basic, underlying mechanisms that result in the perception of pain are different in male and female mice, in male and female nonhuman primates, and in male and female humans."

The findings suggest a new way to approach treating pain conditions, many of which are female prevalent. Migraine and fibromyalgia, for example, have female-to-male ratios of 3:1 and 8 or 9:1, respectively.

Porreca believes preventing -induced nociceptor sensitization in females may represent a viable approach for the treatment of female-prevalent pain disorders, while targeting orexin B-induced sensitization might improve the treatment of pain conditions associated with nociceptor activation in males.

Moving forward, Porreca and his team will continue looking for other sexually dimorphic mechanisms of pain while building on this study to seek viable ways to prevent nociceptor sensitization in females and males. He is encouraged by his recent discovery of a prolactin antibody, which could prove useful in females, and the availability of orexin antagonists that are already Food and Drug Administration-approved for the treatment of sleep disorders.

"We are bringing the concept of precision medicine—taking a patient's genetics into account to design a therapy—to the treatment of pain," Porreca said. "The most basic genetic difference is, is the patient male or female? Maybe that should be the first consideration when it comes to treating pain."

More information: Harrison Stratton et al, Nociceptors are functionally male or female: from mouse to monkey to man, Brain (2024). DOI: 10.1093/brain/awae179


https://medicalxpress.com/news/2024-06-evidence-sex-differences-pain.html

After Texas Win, School-Choice Groups Eye Other Red States

 by Susan Crabtree via RealClearPolitics,

The political ground shifted in Texas last week, and the impact of the electoral shakeup could send aftershocks across the nation for months, if not years, to come.

A wave of Republican incumbents fell to conservative challengers in the Texas House in last week’s primary run-offs, turning an already red legislature crimson and threatening the state House GOP leader’s hold on power. Those who helped lead the intra-party Texas fight now have their sights set on defeating centrist Republicans in other red states, including Tennessee, Georgia, Idaho, and South Carolina.

A concerted joint effort by Gov. Greg Abbott, outside groups, and a deep-pocketed donor flipped the seats of 14 Republicans who had opposed Abbott’s school-choice measure – a state record.

Abbott’s effort to pass school choice died last fall when 21 House Republicans – mostly from rural districts – voted to strip a voucher program out of a larger education bill. Of those 21 voucher opponents, 15 now aren’t returning. The coalition defeated six GOP incumbents in March, then three more in last week’s run-offs. Additionally, the group filled four of the five retiring Republican seats with voucher supporters, and then a voucher backer won a special election run-off.  

The leading factor in these Republicans’ historic defeats hasn’t been making the most national headlines or even the most local news. It’s unrelated to Abbott’s border fight with President Biden, state Attorney General Ken Paxton’s resentment over efforts to impeach him, or even widespread local protests over the state’s skyrocketing property taxes.  

Those issues all played out in the election, but school choice was far and away the most lethal campaign issue across the Lone Star state. Its impact was especially potent considering the totality of political spending and blitz of advertisements focused on school vouchers and related issues dominating the Texas airwaves and inundating inboxes.

Abbott was determined to make good on his threats to boot anti-school voucher Republicans who have blocked his ambitious crusade to give parents taxpayer-funded options to educate their children outside public schools. After several challengers he backed won their run-offs last week, the governor declared victory and announced that the House “now has enough votes to pass school choice.”

While we did not win every race we fought in, the overall message from this year’s primaries is clear: Texans want school choice,” said Abbott. “Opponents can no longer ignore the will of the people.

House Speaker David Phelan, who supported the effort to scrap the school voucher language from the bill last fall, managed to eke out a run-off win by less than 400 votes. But that razor-thin victory likely dooms his chances of holding onto his leadership post next year.

On the national level, Abbott is best known for his immigration showdown with President Biden, which included the deployment of thousands of Texas Guard members to shut down the border and the decision to send busloads of illegal immigrants from the southern border to places like New York, Washington, D.C., and Texas.

Texans, however, are well aware that Abbott has made school vouchers his top priority, pouring more political capital into the vouchers than any other issue in his eight years in office. The sometimes-cautious governor campaigned for reelection on the issue in 2022 and made universal education saving accounts a central theme of his most recent State of the State addresses. The ESAs would use taxpayer funds to provide parents a voucher worth $10,500 a year per student to use at a private school.

Texas teacher unions have staunchly and successfully opposed school-choice bills for years. They say the programs deprive public schools of essential funds and mainly benefit wealthy families who are already sending their children to private schools.

The Texas chapter of the American Federation of Teachers called the school-choice movement a “scam” which eliminates transparency and public accountability.

"When vouchers strip more money away from our already strapped neighborhood schools, the only people who will benefit are the richest parents, who are already sending their children to private schools. For everyone else, vouchers will crowd classrooms and put every member of the school community who keep the hubs of our communities running on the chopping block. And it’s the hardest hit, and often more rural communities, that get left further and further behind," the Texas AFT wrote in a blog post.

Abbott and his allies vigorously rejected those arguments, countering that most parents desperately want and need the funds to choose the best educational path for their children, especially while public school test scores in Texas and across the nation are continuing to fall. He then redoubled their efforts to pass his voucher plan.

The Texas legislature cannot vote on any bill until 60 days into its legislative session unless the governor declares the measure an “emergency item.” Abbott gave the voucher issue this expedited status. He held two special sessions devoted to passing the initiative, including the one last fall in which opponents, including Phelan, stripped it from a bill providing $6 billion in additional funds to Texas public schools. Those funds would have boosted teacher pay and other public school funding – key negotiating chips that still failed to attract enough supporters.

Heading into the fight, opponents were well aware that they could face consequences at the ballot box if they continued to oppose Abbott’s voucher language.

In response to a ballot question in 2022, 88% of GOP primary voters indicated that they support parents’ “right to select schools, whether public or private, for their children, and the funding should follow the student.” Another poll conducted by the University of Houston Hobby School of Public Affairs in January found that 66% of Republican primary voters said they would be less likely to vote for an incumbent who rejected school choice last year.

[Abbott] made it very clear during the special session that there’s an easy way and a hard way,” Dave Carney, the governor’s longtime political strategist, told RealClearPolitics. “The hard way was we’ll pass it in 2025 with a new legislature. They were informed, well-warned.”

Carney said Abbott has done nearly 100 events on school choice so far this year, cutting television, cable, and digital ads and directing millions of digital impressions to targeted audiences. Abbott’s political action committee also paid for advocates to knock on 400,000 across the state.

Still, Abbott had some powerful help, what Carney describes as a seamless, collaborative effort.

“We’re not taking a victory lap yet, because we still have to get through the general election,” he added. “But we’re anticipating to pick up seats.”

Last fall’s voucher defeat attracted national groups with deep pockets, including the American Federation for Children, a national pro-school choice group, and the Club for Growth, a conservative anti-tax group. Along with Abbott’s PAC, the groups spent a combined $27 million to back pro-voucher challengers against incumbents.

A big portion of those funds came from Jeff Yass, a Pennsylvania billionaire and national Republican megadonor who strongly supports school vouchers. Worth nearly $30 billion, Yass is a co-founder and managing director of Susquehanna International Group, a Philadelphia-based trading and investment firm. The firm was an early investor in TikTok, which nearly doubled Yass’ net worth in the years since the pandemic when the app’s popularity soared.

Working with Trump’s education secretary, Betsy DeVos, a longtime proponent of helping parents subsidize private school tuition, Yass has spent tens of millions boosting the issue, channeling $23 million to the DeVos-backed American Federation for Children’s political action committees since 2021.

In December, Yass cut Abbott’s PAC a $6 million check, the largest single donation in Texas history. He’s also a multi-million dollar donor to the Club for Growth, which has long supported Texas Sen. Ted Cruz and Rep. Chip Roy, who represents Austin and San Antonio.

The Club for Growth, through its School Freedom Fund, spent roughly $4 million in the Texas primary and $4 million more in the run-offs, including $1.5 million against Phelan. David McIntosh, the group’s president, credited Abbott with the leadership to take on his fellow Republicans, who blocked school-choice options for Texas’ 5.4 million public school students.

“I give Gov. Abbott a lot of kudos for his leadership,” McIntosh said in an interview. “Many Republican governors don’t want to take on sitting members of their own party and would not have done the same … that was a crucial factor in us being able to win.”

Early in the effort, McIntosh told his team that big victories in Texas would build momentum for similarly aggressive campaigns in other red states, including Tennessee, Georgia, Louisiana, and Indiana.

Texas now shows that you can’t be a conservative Republican and oppose education freedom,” he said. “It’s now a marker for whether somebody is a genuine conservative or not. It’s going to be something the Club and our School Freedom Fund champion for years to come.”

McIntosh says the school choice initiatives align with the group’s conservative economic agenda because giving parents more alternatives to public school creates market pressure in the education system.

“That benefits the kids,” McIntosh said. “They get a better education, and it benefits the parents who have more control over the resources, and [it] takes the education bureaucracy out of the equation. Schools start operating like a business world, saying, ‘Who’s my customer?’ Right now, they don’t have that pressure.”

The American Federation for Children’s Victory Fund, another key group in the school-choice fight, spent $7 million on the Texas primary and run-offs alone – boosting Texas challengers’ campaigns and helping establish school choice as a GOP litmus test.  

“The primary election results in Texas – the Lone Star earthquake – represent the single biggest movement in favor of school choice in modern history, a result that will prove life-changing for countless Texas families,” Tommy Schultz, the group’s CEO, told RCP. “Republicans lost the moment they chose loyalty to unions and corrupt establishment over students.”

Schultz said he and the coalition of school-choice proponents “anticipate that many other states will remember the Lone Star Earthquake ahead of their own primaries and legislative sessions.”

If you’re a candidate or lawmaker who opposes school choice and freedom in education – you’re a target,” he added. “If you’re a champion for parents – we’ll be your shield.”  

Some Texas insiders are already making comparisons to Colorado’s rapid transformation from a Republican-dominated state in the mid-2000s to a Democratic one over a four-year time frame. For years, progressives have touted their success in Colorado in turning a red state blue, an effort by Democratic politicians and outside groups taking advantage of new campaign finance laws and working with donors willing to commit unprecedented resources to promote progressive policies and win local races.

In a book titled, “The Blueprint: How Democrats Won Colorado,” the authors hailed the joint effort as a model for creating permanent Democratic majorities across the country.

Texas was already a solid red state before the school choice fight, but now its legislature has shifted even further to the right, undermining years-long Democratic efforts to cast it as trending purple based on its growing Latino population. Instead, t he school-choice coalition’s Texas successes have sparked a conversation over whether they’ve developed a “redprint” model that can help solidify permanent conservative majorities across the country.

Yet, Carney points out that Abbott isn’t the first governor to target GOP incumbents opposed to school vouchers. Iowa Gov. Kim Reynolds started the trend in 2022 when the Iowa legislature tried to pass school choice but failed by one vote. It was an election year, and Reynolds and school choice advocates challenged six school anti-school choice incumbent lawmakers. They unseated all nine and passed the measure during the next legislative session.

After the string of defeated GOP incumbents in Texas, other governors are already pledging a similar political litmus test. Late last week, Tennessee Gov. Bill Lee vowed to vet future GOP primary candidates in the next election cycle to determine whether they support school choice, although he didn’t commit to working to defeat Republicans who oppose school choice.

This year what I’m talking to candidates about is education freedom and choice for parents,” he told a local broadcast station late last week. “I want to know where new candidates stand on that issue because it’s so important to me, so you’ll see me talking to candidates.”

Earlier this year, Lee said he expected a school choice “revolution” to take place in Tennessee, but those hopes were dashed in March when a school-choice bill died in the state legislature. But given strong GOP voter support for the issue, the state Republican Party is poised to adopt a strongly worded pro-school-choice platform over the next few months, which will ratchet up the pressure on Republican legislators with a history of opposing voucher programs.

The Club for Growth and the American Federation for Children are monitoring Tennessee closely to see if Lee will follow in Reynolds’ and Abbott’s footsteps.

“It’s a hard decision for governors to make, and you hope you can persuade people to do the right thing, and you don’t have to take out incumbents, but I will have to see what they decide to do,” McIntosh said.  

Yet, the most effective advocate for school choice wasn’t Abbott, Reynolds, or any other GOP governor or outside group, Carney argues. That honor, he says, goes to American Federation of Teachers President Randi Weingarten, who fought children’s return to public school during the COVID pandemic and used the global health crisis to extract union concessions for teachers, sparking a parent revolution in the process.

“Most families can’t afford to make that choice to give their kids a different option,” Carney remarked, decrying what he called the public education system’s “Praetorian Guard” who try to keep parents at bay while implementing “woke” programs and teaching methods while students’ test scores continue to plummet.

https://www.zerohedge.com/political/after-texas-win-school-choice-groups-eye-other-red-states