Sunday, August 31, 2025
Standard post-heart attack treatment may not help, even increase women’s chances of dying
This news might break your heart — literally.
A shocking new study found that the go-to treatment doctors have been using to manage heart attacks for the last 40 years may offer no real benefit for many patients.
Even more alarming, the research suggests that women who receive the drug may face a higher risk of complications, including death.
In the US, someone suffers a heart attack — known medically as a myocardial infarction — every 40 seconds. That adds up to a staggering 805,000 Americans each year, according to the CDC.
“Currently, more than 80% of patients with uncomplicated myocardial infarction are discharged on beta blockers,” Dr. Borja Ibáñez, principal investigator of the “REBOOT” trial, said in a statement.
These medications, which work by slowing the heart rate and lowering blood pressure, are often prescribed for at least a year — and in many cases, for life — based on older studies that suggested they could curb the risk of a second heart attack or death.
“Their benefits were linked to reduced cardiac oxygen demand and arrhythmia prevention,” Ibáñez explained, “but therapies have evolved.”
Today, he noted, clogged arteries — the leading cause of heart attacks — can often be quickly reopened thanks to advanced procedures, cutting the risk of serious complications like arrhythmias, or irregular heartbeats.
“In this new context — where the extent of heart damage is smaller — the need for beta blockers is unclear,” he said.
But now, thanks to the REBOOT trial, scientists may finally be getting a better idea.
In the study, Ibáñez and his team enrolled 8,505 heart attack patients from 109 hospitals in Spain and Italy. All of them had suffered a heart attack but retained normal cardiac function afterward.
Half were randomly assigned to take beta blockers after hospital discharge, while the other half were not. Otherwise, every patient received the current standard of care and was followed for nearly four years.
By the end of the study, researchers found no major differences in the rate of death, repeat heart attacks or hospitalizations for heart failure between the two groups.
That’s a major blow to a treatment long considered routine, raising serious doubts about whether the drug actually benefits patients with normal heart function — who make up about 80% of survivors after a first heart attack.
Although generally considered safe, beta blockers can cause side effects like fatigue, a low heart rate, and sexual dysfunction.
“While we often test new drugs, it’s much less common to rigorously question the continued need for older treatments,” Ibáñez said.
“The trial was designed to optimize heart attack care based on solid scientific evidence and without commercial interests,” he added, noting it was conducted with no funding from the pharmaceutical industry.
Digging deeper into the data, researchers uncovered a shocking twist: women with minimal cardiovascular damage after their heart attacks who took beta blockers actually fared worse.
These women faced a higher risk of suffering another heart attack — which is far more dangerous than the first — or being hospitalized for heart failure compared to those who skipped the drug.
In fact, their chances of dying were 2.7% higher during the follow-up period.
Notably, however, this increased risk didn’t appear in women who suffered mild heart damage after a heart attack.
Men also showed no signs of this heightened danger after taking beta blockers.
“That’s actually not surprising,” Dr. Andrew Freeman, director of cardiovascular prevention and wellness at National Jewish Health, told CNN Health.
“Gender has a lot to do with how people respond to medication. In many cases, women have smaller hearts. They’re more sensitive to blood pressure medications. Some of that may have to do with size, and some may have to do with other factors we have yet to fully understand,” he explained.
The researchers also pointed out that women in the REBOOT trial were generally older, sicker and got less aggressive treatment for heart attacks than men. All of these factors, they said, could help explain their higher risk.
Still, Ibáñez said the study will “change clinical practice worldwide,” calling the findings “one of the most significant advances in heart attack treatment in decades.”
“These results will help streamline treatment, reduce side effects, and improve quality of life for thousands of patients every year,” he added.
https://nypost.com/2025/08/30/health/standard-post-heart-attack-treatment-may-not-actually-help/
Von der Leyen says Europe is drawing up 'precise' plans to send troops to Ukraine, FT reports
Europe is drawing up "pretty precise plans" for a multinational troop deployment to Ukraine as part of post-conflict security guarantees that will have the backing of U.S. capabilities, European Commission President Ursula von der Leyen told the Financial Times in an interview published Sunday.
“President Trump reassured us that there will be (an) American presence as part of the backstop,” von der Leyen told the FT, adding that “That was very clear and repeatedly affirmed.”
The deployment is set to include potentially tens of thousands of European-led troops, backed by assistance from the U.S., including control and command systems and intelligence and surveillance assets, the report said, adding that this arrangement was agreed at a meeting between U.S. President Donald Trump, Ukrainian President Volodymyr Zelenskiy and senior European leaders last month.
European leaders, including German Chancellor Friedrich Merz, UK Prime Minister Keir Starmer, NATO Secretary-General Mark Rutte and von der Leyen are expected to gather in Paris on Thursday, at the invitation of French President Emmanuel Macron, to continue the high-level discussions on Ukraine, the FT reported, citing three diplomats briefed on the plans.
https://uk.news.yahoo.com/von-der-leyen-says-putin-125347525.html
Maritime agency says it received report of incident southwest of Saudi Arabia's Yanbu
The United Kingdom Maritime Trade Operations reported an incident involving a vessel near Yanbu, Saudi Arabia. The vessel experienced a splash and a loud bang from an unknown projectile. Fortunately, the crew remained unharmed, and the vessel proceeded with its journey.
Xi Made Four Suggestions to Deepen India Ties, Misri Says
Chinese President Xi Jinping, in his bilateral meeting with Indian Prime Minister Narendra Modi on Sunday, made four suggestions to deepen ties between the two countries, a top Indian official said.
Xi called for stronger “strategic communication” and deepening mutual trust, India’s Foreign Secretary Vikram Misri told reporters in Tianjin, China where the two leaders met on the sidelines of a regional security and economic summit. Xi also called for expanding cooperation to “achieve mutual benefits and win-win results,” to accommodate each others concerns, and to “strengthen multilateral cooperation to safeguard common interests,” Misri said.
Labor Day Letdown As East Coast Beaches Close Due To Contamination
Some of the East Coast’s most popular beaches, stretching from Long Island all the way down to Florida, will be off-limits to swimmers this Labor Day weekend thanks to sky-high levels of fecal contamination, officials warned.
On Long Island, Benjamin’s Beach in Bay Shore, a favorite summer spot along the Great South Bay, was slapped with a swimming ban earlier this week after Suffolk County officials found bacteria levels above acceptable safety limits.
Health officials warned that swimming in poo water can result in gastrointestinal illness, rashes and infections of the eyes, ears, nose and throat, and urged residents to stay out of the water until testing shows it’s safe.
Meanwhile, beaches from Crystal River, Fla., to Cape Cod, Mass., and Ogunquit, Maine, have also been slapped with advisories tied to bacteria linked to fecal matter, threatening to spoil swimmers’ holiday fun.
The culprit? A nasty mix of urban runoff, sewage overflows and factory farm waste that’s been pushing dangerous pathogens straight into America’s waters, according to the nonprofit Environment America, the Daily News reports.
The group’s latest report paints a disturbing picture: more than 60% of all U.S. beaches, and 54% along the East Coast, had potentially unsafe contamination levels last year.
“In 2024, 1,930 of 3,187 beaches tested nationwide (61%) experienced at least one day when indicators of fecal contamination hit potentially unsafe levels — exceeding the EPA’s most protective standards,” the report warned.
And if that wasn’t gross enough, Suffolk County officials are also telling locals to stay far away from Prestons Pond near Manorville, where a fresh bloom of toxic blue-green algae has made the water hazardous.
Contact with the slime can cause rashes, nausea, vomiting, diarrhea and even trouble breathing, according to the New York State Department of Health.