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Tuesday, September 2, 2025

RFK Jr. Sets CDC Priorities in Op-Ed After Leadership Shake-Up

 


Health and Human Services Secretary Robert F. Kennedy Jr. said the Centers for Disease Control and Prevention should return its focus to tracking infectious diseases and pandemic response less than one week after the agency’s director was fired.

Kennedy outlined six priorities in a Wall Street Journal opinion piece on Tuesday including “enhancing scientific rigor” through “ensuring America leads the world in safe, effective vaccines and trusted guidance.” On Aug. 27, Kennedy fired CDC director Susan Monarez after a confrontation over vaccine policy. Monarez was confirmed to lead the agency by the Senate in July.

https://www.bloomberg.com/news/articles/2025-09-02/rfk-jr-sets-cdc-priorities-in-op-ed-after-leadership-shake-up

Gilead eyes price hikes for HIV meds in state AIDS programs

Gilead (GILD) stock in focus as the company eyes major price hikes for key HIV drugs supplied for state AIDS Drug Assistance Programs.
https://seekingalpha.com/news/4491391-gilead-eyes-price-hikes-hiv-meds-state-aids-programs

 

US strike obliterated ‘drug-carrying boat’ off Venezuela, killing 11 Tren de Aragua ‘Narcoterrorists’

 President Trump shared dramatic footage of the US military obliterating a boat carrying drugs and Tren de Aragua gangbangers off the coast of Venezuela on Tuesday. 

The video showed the small boat being blown out of international waters and exploding into flames after it was struck by a single missile, killing all aboard.

Trump said the boat was occupied by 11 “Tren de Aragua Narcoterrorists” and was en route to the US when it was blown to smithereens.

The video at first shows the boat cruising along.TruthSocial / @realDonaldTrump
The clip then shows the strike.TruthSocial / @realDonaldTrump

“TDA is a designated Foreign Terrorist Organization, operating under the control of Nicolas Maduro, responsible for mass murder, drug trafficking, sex trafficking, and acts of violence and terror across the United States and Western Hemisphere,” Trump wrote on Truth Social.


The ship explodes instantly.TruthSocial / @realDonaldTrump

“No U.S. Forces were harmed in this strike. Please let this serve as notice to anybody even thinking about bringing drugs into the United States of America. BEWARE!”

This is the first known attack on a cartel since Trump authorized the military to carry out such operations earlier this year.

The region is a major exporter of cocaine, but initial statements did not reveal the type of drug or drugs that the boat was smuggling.

Trump in late August deployed three guided-missile destroyers and about 4,000 Marines to the Venezuelan coast — prompting the country’s authoritarian left-wing leader Nicolas Maduro to mobilize millions of militia members and claim an invasion was imminent

The Trump administration has branded the Cuba-aligned strongman, in power since 2013, as a drug cartel leader and fugitive from justice. 

The US government in early August offered a $50 million reward for information leading to Maduro’s arrest. 

On Monday, Maduro accused the US of seeking a regime change in his country amid a naval buildup in the Caribbean.

“They are seeking a regime change through military threat,” Maduro told journalists, officials and uniformed military brass in Caracas, echoing comments last week by his government’s representative at the United Nations.

“Venezuela is confronting the biggest threat that has been seen on our continent in the last 100 years,” Maduro said. “A situation like this has never been seen.”

Maduro said Venezuela was “super prepared” and would not bow to threats from the US.

“Maduro’s reign of terror is ending,” a source close to the administration told The Post Tuesday in response to the strike.

“And President Trump’s historic mission to secure the Western Hemisphere is just getting started.”

https://nypost.com/2025/09/02/world-news/footage-shows-us-strike-that-obliterated-drug-carrying-boat-off-venezuela-killing-11-tda-narcoterrorists/

Ukraine Urges China To Pressure Putin As War Overshadows SCO Summit

 by RFE/RL staff via OilPrice.com,

  • Ukraine called on China to take a more active role in pressuring Russia toward peace as Putin arrived in Beijing after the SCO summit.

  • Kyiv criticized the summit’s Tianjin Declaration for omitting any reference to the war in Ukraine.

  • European leaders plan to meet in Paris to discuss security guarantees for Ukraine, while Trump’s proposed trilateral peace summit remains uncertain.

Ukraine urged China to pressure Vladimir Putin to move toward peace as the Russian president arrived in Beijing following his participation in the Shanghai Cooperation Organization (SCO) summit -- where he defended the war that has killed tens of thousands of people.

"Given the significant geopolitical role of the People's Republic of China, we would welcome a more active role [for Beijing] in bringing peace to Ukraine based on respect for the UN Charter," Ukraine's Foreign Ministry said in a statement as Putin arrived in the Chinese capital on September 2.

The ministry statement noted that the SCO’s final declaration avoided mention of the conflict, which has become a full-scale war since Russia’s February 2022 invasion of Ukraine.

“We consider it eloquent that the main final document of the summit, the 20-page Tianjin Declaration, does not contain a single mention of the Russian war against Ukraine,” the statement said.

“It is surprising that the largest war of aggression in Europe since World War II was not reflected in such an important, fundamental document, while it mentions a number of other wars, terrorist attacks, and events in the world.”

It said the failure to mention Russia’s war in Ukraine in the declaration “indicates the failure of Moscow's diplomatic efforts.”

Ukrainian President Zelenskyy has consistently called on China -- a close ally of Russia -- to put pressure on Putin to end the war.

Another high-profile diplomatic event in China will be held on September 3 -- a massive military parade commemorating the 80th anniversary of the end of World War II. Many leaders -- including Putin -- are remaining in China after the SCO to attend the parade.

Putin Blames The West

At the SCO in Tianjin outside of Beijing, Putin sent a defiant message against the West over his invasion of Ukraine after standing shoulder-to-shoulder with Chinese leader Xi Jinping.

Putin said the war in Ukraine came about “not as a result of a Russian attack” but because of a Western-backed coup in Kyiv, according to comments carried by the Russian news agency TASS.

That was an inaccurate reference to the Maidan protests that pushed Moscow-friendly Ukrainian President Viktor Yanukovych from power in 2014, after he scrapped plans for a trade agreement with the EU and turned toward Russia instead.

Putin added that what he called the West’s attempts to draw Ukraine into NATO posed a "direct threat to Russia’s security," a claim that the military alliance has repeatedly denied.

Meanwhile, Kyiv's European allies in the so-called Coalition of the Willing -- led by French President Emmanuel Macron and British Prime Minister Keir Starmer -- are set to meet in Paris on September 4 to discuss potential security guarantees for Ukraine.

"Together with our partners, and in coordination with NATO, we will work to define robust security guarantees for Ukraine. These are a necessary prerequisite to move credibly towards peace," Macron wrote on X following talks with NATO chief Mark Rutte.

"We will also review Russia’s stance, as it persists in its war of aggression and continues to reject peace," Macron added.

European Commission President Ursula von der Leyen on August 31 said Kyiv's European allies were working on “pretty precise plans” and a "clear road map" for a potential deployment of troops to Ukraine should a peace deal be struck between Kyiv and Moscow.

Von der Leyen, in comments published in The Financial Times, added that any such venture would have the full backing of the United States, which has swayed back and forth on potential involvement over the past year.

'No Concrete Plans' For Trilateral Summit

Separately, on the sidelines of the SCO, Kremlin foreign policy adviser Yury Ushakov said there were no immediate plans for a trilateral meeting between Putin, Zelenskyy, and US President Donald Trump, contradicting recent remarks by Trump that he was arranging such a meeting.

"Now everyone is talking about a trilateral summit...but there has been no concrete agreement on this between Putin and Trump," Ushakov said.

Trump, who has made ending the war a top priority of his administration, has grown increasingly frustrated with Putin's refusal to meet with Zelenskyy but has suggested he was moving toward a trilateral meeting with himself included.

Trump has also expressed anger with Russia's nonstop campaign of air assaults on Ukrainian cities, causing civilian deaths and damage to infrastructure.

On September 2, Mykola Kalashnyk, head of the regional military administration, said an overnight Russian air strike on the city of Bila Tserkva near Kyiv killed one person and created a massive blaze at a multistory building. Attacks were also reported near the cities of Chernihiv and Sumy.

Inside Russia, the Rostov regional governor reported early on September 2 that some 320 people were evacuated from an apartment block after a Ukrainian drone attack. Details were not immediately available.

https://www.zerohedge.com/geopolitical/ukraine-urges-china-pressure-putin-war-overshadows-sco-summit

'Enough Is Enough: What A CDC Resignation Letter Reveals'

 by James Lyons-Weiler via The Brownstone Institute,

When Demetre Daskalakis resigned as Director of the National Center for Immunization and Respiratory Diseases at CDC, his letter to leadership carried a tone of finality and moral conviction. 

“Enough is enough,” he declared, explaining that Secretary Robert F. Kennedy, Jr.’s leadership had made it impossible for him to continue. The letter has been praised as principled, but when read closely it is less a defense of science than a portrait of the very rhetorical habits that drove the public away from CDC in the first place: appeals to authority, catastrophic predictions, ad hominem attacks, and factual distortions.

Consider his charge that he can no longer serve in an environment that “treats CDC as a tool to generate policies and materials that do not reflect scientific reality and are designed to hurt rather than to improve the public’s health.” 

This is a false dichotomy. It frames the choice as binary: either one accepts CDC’s “scientific reality,” or one is accused of designing policies to harm.

Yet the last five years have shown what most Americans already know: what CDC has called “science” has often been neither transparent nor replicable, but political judgment dressed in a white coat. 

He accuses the new HHS of narrative enforcement, when, in reality, CDC has become infamous for the same partly on his watch.

Lockdowns, school closures, and vaccine mandates were not the inevitable products of neutral science — they were policy choices, frequently contradicted by the very data the CDC refused to release. Kennedy did not cause that collapse of trust. Power overreach and failed policy did.

Still, Daskalakis appeals to institutional sanctity: “unvetted and conflicted outside organizations seem to be the sources HHS use over the gold standard science of CDC.” 

But the claim that CDC represents “gold standard science” rings hollow. The agency’s failures are well documented: contaminated Covid tests that delayed early detection, failure to use standard qRT-PCR to control for false positives, shifting guidance on masks that left the public whiplashed, withheld vaccine safety data buried in VAERS and VSD, and FOIA evasions that stonewalled independent scrutiny. To describe this record as “gold standard science” is an appeal to authority wholly unsupported by the evidence.

The catastrophism in his letter is striking but rings hollow. He warns that Kennedy’s policies will “bring us to a pre-vaccine era where only the strong will survive and many if not all will suffer.” He’s pretending that Kennedy has said he wants no vaccines for anyone. This is a combined fallacy: false dichotomy and slippery slope. Questioning the safety of excipients, the timing, number, or necessity of vaccines does not condemn the country to Darwinian misery. 

In fact, mortality from infectious diseases like measles, pertussis, and diphtheria had already declined long before mass vaccination, thanks to sanitation, nutrition, and reduced exposure to livestock reservoirs. The fact of loss of protection due to waning immunity is not found in his resignation. Balanced debate about risks and benefits does not mean “returning to the dark ages.” It means practicing science as it should be — open, skeptical, and transparent and will full accountability on scientific claims.

At points, the rhetoric becomes openly hostile. ACIP members are dismissed as “people of dubious intent and more dubious scientific rigor,” and Kennedy himself is cast as an “authoritarian leader.” These are ad hominem attacks, not arguments. They dismiss individuals rather than engage with data or reasoning.

I’ve worked with Secretary Kennedy long enough to know him as a sensitive, thoughtful, non-reactionary, considerate leader. He is so considerate it can at times nearly irk his underlings who would like to see him come to decisions faster. But that’s because they have already made up their minds. Kennedy works arbitrarily and uses contrarianism – debate, adversarial set-ups – to hammer out the details until the description of a problem and its solution fits the mold. I’ve never heard of anyone spun out of his orbit for doing due diligence-based dissent. Meanwhile, Daskalakis pines for the old “following the leader” model of authoritarian “trust the science” CDC. Those days are gone.

The gravest claim in the letter is that “eugenics plays prominently in the rhetoric being generated.” Daskalakis gives us no quotations, policies, or documents. Sometimes words just sound right when one is upset, I suppose. Ironically, the accusation is not only unsubstantiated but inverted. Kennedy has consistently warned against coercive health policies and corporate capture, both of which he argues worsen inequality. To portray his emphasis on transparency and medical freedom as eugenics is a straw man — a distortion intended to silence rather than to debate.

Daskalakis goes further, blaming Kennedy for violence: “I am resigning because of the cowardice of a leader that cannot admit that his and his minions’ words over decades created an environment where violence like this can occur.” 

This refers to a shooting at CDC. Again, no hint of evidence has been offered by Daskalakis or anyone else to connect Kennedy’s words to the crime. It is a post hoc fallacy, exploiting tragedy to smear a political opponent. It’s shameless and ripens the fruit of his letter to rot.

Perhaps most jarring is his claim that Kennedy’s HHS has sought to “erase transgender populations, cease critical domestic and international HIV programming, and terminate key research to support equity.” 

The rhetoric here is catastrophic, baseless, and false. In reality, under Dr. Jay Bhattacharya’s leadership, the NIH has made HIV a top research priority. Far from “ceasing HIV programming,” Kennedy’s administration has pledged to tackle the epidemic with fresh eyes, free from the pharmaceutical capture that distorted earlier approaches. To suggest otherwise is not just hyperbole; it is disinformation.

Daskalakis also insists he has “always been first to challenge scientific dogma.” His self-nomination as a leader in this activity is again unsupported by evidence. Did Daskalakis speak up when Moderna and Pfizer inflated their efficacy estimates? Did Daskalakis write a letter of complaint when CDC reported that 20 layers of cloth masks, no 16, no, thank you Dr. Fauci, only 1 layer of cloth mask was sufficient to stop the SARS-CoV-2 virus in its tracks? I could go on, but the answer is not one peep from this challenger of dogma.

And yet, in practice, his defense of CDC orthodoxy shows the opposite. The real challenger of dogma has been Kennedy, who has questioned the sacred cows of American public health — vaccine trial design, regulatory capture, chronic disease drivers, and the silencing of dissent. What Daskalakis calls “dogma” is only that which challenges the CDC. What he calls “science” is whatever the CDC itself declares. Policy-first narrative enforcement activities.

None of this is to deny the human element. Daskalakis thanks his colleagues as “dedicated professionals committed to improving the health and well-being of communities across the nation.” 

Burnout and disillusionment are real, and his sense of betrayal is palpable. But compassion must extend beyond the walls of the CDC. For decades, the American people have suffered from rising chronic illness. Six in ten live with at least one chronic disease. Life expectancy has declined relative to peer nations. Autoimmune conditions, autism, and metabolic disorders have surged. To claim that Kennedy caused mistrust is to invert reality: mistrust grew because what CDC did was not science but policy, enforced without transparency, accountability, or humility.

The refrain “enough is enough” was meant as a rebuke of Kennedy’s HHS. But for the American people, it applies first and foremost to the CDC itself. Enough of secrecy disguised as science. Enough of fear-based rhetoric to silence dissent. Enough of sanctimony about “gold standards” while health outcomes decline due to medicine optimized to proxy outcomes. Kennedy’s critics mistake his reforms for authoritarianism when, in fact, they are the first genuine challenge to authoritarian policy disguised as medicine.

The resignation of a career official should not be mocked. But it should be read for what it is: a defense of a failed paradigm, framed as a moral stand. The task ahead is not to preserve the CDC’s aura; that is undeserved. It is instead to put public health on a foundation of honesty, openness, and freedom worthy of trust. That — not resignation letters steeped in fallacy — is what will truly make America healthy again.

https://www.zerohedge.com/political/enough-enough-what-cdc-resignation-letter-reveals

Vertex forges $2B-plus alliance with Enlaza to create new autoimmune drugs

 Vertex Pharmaceuticals is offering Enlaza Therapeutics more than $2 billion in biobucks through a multi-target drug discovery deal aiming to create new T-cell engagers and small-format drug conjugates.

Initially, Vertex is paying the California biotech $45 million, which includes an upfront payment and equity investment, according to a Sept. 2 release. In exchange, Vertex will work with Enlaza’s tech platform, dubbed War-Lock, which is designed to use synthetic biology in efforts to build potentially first-in-class covalent biologics.

The freshly linked pair is chasing new drugs to treat undisclosed autoimmune diseases and also to improve conditioning regimens for sickle cell disease and beta thalassemia. More gentle conditioning would benefit Vertex, which sells Casgevy, a CRISPR/Cas9 gene-edited therapy approved in both sickle cell disease and beta thalassemia.

Enlaza is expected to head up all research activities through development candidate nomination, according to the terms of the four-year pact. Vertex will then take the reins for all future R&D, manufacturing and commercialization of successful product candidates, according to the release.

Boston-based Vertex will bankroll all R&D efforts related to the pact. The biopharma is also offering Enlaza more than $2 billion in future milestone payments, plus royalties.

For Enlaza, the partnership represents a move into the autoimmune space. The company said it had several preclinical cancer candidates in 2024, when the biotech raised $100 million in series A money.

The biotech touts itself as the “first covalent biologics platform company,” with big-name backers such as J.P. Morgan Asset Management’s Private Capital life sciences group, Frazier Life Sciences, Amgen, Regeneron and Alexandria Venture Investments joining in on last year’s fundraise.

Enlaza’s War-Lock platform is designed to create “highly specific warheads” that covalently bind to drug targets, according to the biotech.  

For Vertex, the deal announcement shortly follows the termination of company efforts to follow up on its non-opioid pain reliever, Journavx (suzetrigine). The biopharma axed its investigational sodium channel inhibitor after the asset failed to outpace placebo at improving pain scores in a phase 2 trial.

The company also laid off 125 staffers this summer, a move tied to the cancelled development of Vertex’s VX-264, a “cells plus device” therapy prospect for type 1 diabetes. The approach involved creating insulin-producing cells and surgically implanting them into patients.

The biopharma abandoned VX-264 after the cell-device combo failed to improve a diabetes biomarker in a phase 1/2 trial. The discontinuation triggered an impairment charge of $379 million, according to a May earnings report.

The company is still continuing development for another islet cell therapy, which successfully reduced dangerously low blood sugar levels in a phase 1/2 test.

https://www.fiercebiotech.com/biotech/vertex-forges-2b-alliance-enlaza-create-new-autoimmune-drugs-improve-conditioning-methods

Cigna’s Evernorth invests $3.5B in ex-Walgreens specialty pharmacy

 

  • Cigna’s health services division Evernorth has invested $3.5 billion in Shields Health Solutions as the company continues to build out its lucrative specialty pharmacy business.

  • Shields, which helps hospitals and other providers create and manage their own specialty pharmacies, is one of five standalone businesses created from pharmacy behemoth Walgreens, which was acquired and chopped up by private equity firm Sycamore Partners last week.

  • Evernorth’s investment in the form of preferred stock does not give Evernorth a controlling stake in Shields and is not expected to materially impact Cigna’s earnings guidance for 2025. The deal does give the company the option to invest more in Shields in the future.


Specialty drugs are expensive prescription medicines for complex and chronic conditions that are only dispensed through specialized pharmacies like Shields. Less than 5% of the U.S. population takes specialty drugs, according to industry estimates, but the prescriptions account for more than 50% of total U.S. pharmacy spend.

Margins on specialty drugs can be equivalent to or lower than those of non-specialty medicines. But since their list price is significantly higher, specialty drugs can result in profits of hundreds or even thousands of dollars per prescription.

As such, specialty pharmacy is a major driver of revenue and profit for pharmacy benefit managers like Cigna’s Express Scripts — a business housed under its Evernorth division — and for their parent companies. On a recent earnings call, Cigna executives attributed higher-than-expected Evernorth earnings in part to strong momentum in its specialty and care services platform.

Similarly, Shields was one of Walgreens’ most lucrative business lines before the beleaguered retailer sold to Sycamore in a $10 billion deal that closed last week.

Shields brought in slightly below $700 million in revenue over the last twelve months, up from $212 million in 2021, according to estimates from J.P. Morgan analyst Lisa Gill. Moreover, the specialty pharmacy also boasts strong profit margins, with adjusted operating income estimated at more than $200 million for the 2024 fiscal year.

The numbers are fueled by rising demand for specialty drugs. Employers say the trend is a major driver of spiking healthcare costs as conditions like cancer become more prevalent, driving higher prescribing of complicated and expensive medications to treat them.

https://finance.yahoo.com/news/cigna-evernorth-invests-3-5b-084916317.html