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Thursday, January 22, 2026

ImmunityBio Rises Again As Short-Sellers Face Losses

 ImmunityBio (

IBRX+7.22%), which develops immunotherapies for cancers and infectious diseases, closed Wednesday at $6.92, up 6.79%. The stock moved higher as short-sellers considered what to do after the company’s share price tripled in just three weeks this year. Trading volume reached 93.5 million shares, about 357% above its three-month average of 20.5 million shares. ImmunityBio IPO'd in 2015 and has fallen 80% since going public.

How the markets moved today

The S&P 500 gained 1.16% to finish Wednesday at 6,875, while the Nasdaq Composite added 1.18% to close at 23,225. Within biotechnology, peers Nkarta closed at $2.2 (+7.84%) and Allogene Therapeutics ended at $1.6 (+1.91%), underscoring ongoing interest in higher-risk drug developers.

What this means for investors

ImmunityBio’s incredible run continued today as short-sellers considered closing their positions in the stock following a tremendous batch of news over the last two weeks. Today’s 7% share price increase doesn’t really tie to any specific news, but likely stems from a certain amount of these short-sellers covering their positions following recent positive developments.

Bloomberg reports that short-sellers now face a nearly $500 million paper loss on the stock following its rise, thanks to 35% of its public float being held short before this year’s run. Billionaire Patrick Soon-Shiong, ImmunityBio’s chief scientist, medical officer, and executive chairman, explained, “It was hard for me to understand how you would short a stock for a company trying to find a cure for cancer.” 

https://www.fool.com/coverage/stock-market-today/2026/01/21/stock-market-today-jan-21-immunitybio-rises-again-as-short-sellers-face-losses/

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