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Sunday, April 6, 2025

Torres pushes Hochul to crack down on illegal vapes from China

 Gov. Kathy Hochul should ramp up New York enforcement against illegal-flavored cigarettes and vapes coming from China that end up in the hands of New York’s teens, a rival Democrat said.

Rep. Ritchie Torres, who sits on the House Select Committee on the Communist Party, urged Hochul to amend state law to allow the Tax Department to bolster the state’s anemic enforcement, now led by the Health Department.

“I urge your administration to take decisive action to strengthen enforcement against the sale of illegal flavored e-cigarettes, particularly those originating from China, by granting the New York Department of Taxation and Finance authority alongside the Department of Health,” Torres said in a March 30 letter to the governor.

Rep. Ritchie Torres urged Hochul to amend state law to allow the Tax Department to bolster the state’s anemic enforcement, now led by the Health Department.Bloomberg via Getty Images

New York banned flavored vapes in 2020, but the products continue to flood the market, Torres said, undermining public health efforts.

He complained the vapes, often disguised under misleading labels and shipped through unauthorized channels, are “designed to appeal to minors while evading both state and federal regulations.

“These products pose a direct threat to public health, with dangerously high nicotine concentrations and unknown chemical additives,” Torres said in the letter to Hochul. “The persistence of illegal flavored vapes not only fuels nicotine addiction among young people but also burdens state enforcement agencies that lack the necessary authority and resources to effectively crack down on these illicit operations.”

The law also should be strengthened to classify flavored vapor products as contraband, thus allowing Tax Department officers to confiscate vapes from any business or shipment, just as they do for unstamped cigarettes, the congressman said.

The rival Democrat said Gov. Kathy Hochul should ramp up New York enforcement against illegal-flavored cigarettes and vapes coming from China.Aidin Bharti/Office of Governor Kathy Hochul

“This expansion of authority will ensure that both Health and Tax enforcement agencies are actively investigating and penalizing illegal flavored vape sales, thereby increasing the likelihood of identifying and prosecuting violators,” said Torres, who is eyeing a primary against Hochul in 2026.

New York’s fight against tobacco has dramatically curbed youth smoking, Torres noted, but the continued availability of illicit flavored vapes threatens to “reverse these gains.”

“By taking bold action to enhance enforcement, close regulatory loopholes, and curb the flow of illegal products, we can protect public health, uphold the integrity of state laws, and safeguard critical tax revenues,” he said in the letter to the governor.

More than eight out of 10 current e-cigarette users used flavored e-cigarettes, with fruit flavors being the most popular.Getty Images

About 6% or 1.63 million middle and high schoolers in the US say they use vapes, according to a survey released last fall by the federal Food and Drug Administration.

More than eight out of 10 current e-cigarette users — 87.6% — used flavored e-cigarettes, with fruit flavors being the most popular, followed by candy, desserts, or other sweets, mint and and menthol, the survey showed.

As part of Mayor Eric Adams’ Operation Padlock aimed at shutting down illegal cannabis shops, New York City authorities discovered that many of the illicit merchants were also selling outlawed e-cigs — leading to the seizure and destruction of 1,200 lbs. of vape products last fall.

The city also filed suit to snuff out illegal vape wholesalers.

Last October, the FDA, in collaboration with US Customs and Border Protection , seized 3 million units of illegal e-cigarette products, with an estimated retail value of $76 million.

The seizures were part of a joint operation to inspect incoming shipments and prevent illegal e-cigs from entering the country.

All the shipments came from China and were mislabeled to evade detection, federal authorities said.

Asked about Torres’ pitch, a Hochul spokesperson responded, “New York is a national leader in its enforcement against illegal and dangerous e-cigarettes. The governor will review any related legislation that passes both houses of the legislature.” 

https://nypost.com/2025/04/06/us-news/ritchie-torres-pushes-hochul-to-crack-down-on-illegal-chinese-vapes/

NY bill would ban cops from routine traffic stops like one that nabbed famous serial killer

 A new bill would ban cops in the state from stopping and searching drivers over a slew of low-level violations — including the one that ended up nabbing serial killer Joel Rifkin.

Top law-enforcement officials are calling the Albany proposal the “most dangerous” and “craziest” bill they have ever seen, warning it would limit cops’ ability to conduct routine traffic stops that can uncover much more serious crimes.

“It is the most ridiculous thing I have seen in my 36 years in law enforcement,” Nassau County District Attorney Anne Donnelly told reporters Friday outside of the county’s police memorial in Mineola, LI.

District Attorney Anne T. Donnelly and Nassau County Police Commissioner Patrick Ryder addressing the media about a multi-million-dollar money laundering investigation in Mineola, NY
Nassau County District Attorney Anne Donnelly called the proposal “ridiculous.”Dennis A. Clark

The proposed legislation would no longer allow officers to stop or search drivers over such issues as busted head or tail lights, expired registrations and inspections, window tints and even the smell of marijuana.

Donnelly said she believes the bill would disproportionately impact Nassau County because of the region’s high number of drivers and car accidents, allowing scofflaws and criminals to essentially break the law and get away with it.

She brought up the fact that Rifkin murdered at least 17 people in the area before being uncovered in 1993 during a traffic stop over the missing license plate on the rear of his tan Mazda pick-up truck — which was hiding a body in its trunk.

“When an officer walks up to a driver and asks them for their license and registration — they never know what is going to happen next,” Donnelly said. “It’s important to be able to make these legitimate stops. There is no such thing as a routine traffic stop.”

But supporters of the bill argued it’s a necessary step toward promoting racial equity and preventing unnecessary police encounters, especially in Nassau — which has an active lawsuit against the county claiming that the police have “acted with racial bias” when making traffic stops.

Though black and Latino residents make up under 30% of the county’s population combined, police data show they account for 61% of arrests, 50% of traffic stops, 60% of field interviews and 69% of pat-downs.

Police officer from highway traffic patrol pulling over a vehicle and approaching the driver for license and registration.
The new bill would ban cops in the state from stopping and searching drivers over a slew of low-level violations.Gorodenkoff – stock.adobe.com

White drivers on average also receive 1.3 tickets per stop compared to two tickets for black drivers and 2.1 for Latino drivers.

Nassau County Executive Bruce Blakeman called that argument “ridiculous,” and said most of the time a stop is made, police are unaware of the driver’s race beforehand.

“It’s just a bizarre argument, it’s pro-criminal,” Blakeman said. “It doesn’t matter what race you are. If you’re breaking the law then you’re breaking the law.”

Nassau Police Commissioner Patrick Ryder said that most of the time, low-level infractions such as broken lights or expired registrations result in warnings, but not having the power to enforce the law makes the roads less safe.

“They say the roads are so bad in Nassau County. Well, you would just be taking another tool away from us that’s going to get these bad drivers off the road,” he said. “Stop taking the handcuffs off of the criminals and putting them onto our men and women in law enforcement.”

State Sen. Brady Hoylman-Sigal, who sponsored the bill, did not respond to The Post’s request for comment.

Gov. Kathy Hochul’s office did not respond, either.

https://nypost.com/2025/04/06/us-news/ny-bill-would-ban-cops-from-routine-traffic-stops-like-the-one-that-nabbed-a-serial-killer-most-dangerous-ever/

Alzheimer's Lecanemab Treatment Up to 36 Months Supported by Extension Study

 Biomarker and cognitive data supported treatment with the anti-amyloid agent lecanemab (Leqembi) for up to 36 months in early Alzheimer's disease, initial findings from the CLARITY AD open-label extension study suggested.

Continuous treatment led to greater changes in plasma amyloid-beta 42/40 levels, reported Christopher van Dyck, MD, of Yale University in New Haven, Connecticut, in a poster presented at the American Academy of Neurologyopens in a new tab or window (AAN) annual meeting.

Cognitive trajectories also appeared better with lecanemab treatment based scores from three assessments -- the Clinical Dementia Rating-Sum of Boxes (CDR-SB), the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog 14), and the Alzheimer's Disease Cooperative Study-Activities of Daily Living Scale for Mild Cognitive Impairment (ADCS MCI-ADL) -- for up to 36 months.

To assess cognitive changes, the researchers compared the lecanemab-treated group in the open-label extension against a matched cohort from the Alzheimer's Disease Neuroimaging Initiative (ADNI). During the placebo-controlled period of CLARITY AD, the ADNI cohort and the placebo group had a similar cognitive trajectory.

In the open-label extension, a responder analysis suggested that lecanemab delayed progression to the next Alzheimer's stage based on CDR-SB scores by 30% (HR 0.704, 95% CI 0.59-0.84).

A subgroup of participants with low or no tau -- below 1.06 standardized uptake value ratio (SUVR) on PET -- showed that most maintained or showed improvement on CDR-SB scores with continued lecanemab treatment. Results for ADAS-Cog 14 and ADCS MCI-ADL in the low-tau subgroup were generally consistent with CDR-SB trends.

Serious adverse events occurred in 20.5% of the total sample of 1,616 people in the core CLARITY AD trial and the open-label extension study who received lecanemab. Amyloid-related imaging abnormalities with edema (ARIA-E) occurred in 14.7%, ARIA with hemosiderin deposits (ARIA-H) occurred in 23.8%, and intracerebral hemorrhage (ICH) occurred in 0.7%. Three deaths concurrent with ARIA or ICH occurred.

"These findings provide the first evidence for a continued benefit of lecanemab and disease modification over the long term, out to 36 months," van Dyck told MedPage Today.

"They also suggest that individuals with lower pathology -- no or low tau, or low amyloid -- experience a particularly robust stabilization of symptoms," he continued. "These results collectively underscore the importance of early initiation and continued long-term treatment."

Lecanemab, which binds with high affinity to soluble amyloid-beta protofibrils, was approvedopens in a new tab or window to treat early Alzheimer's disease based on findings from the phase III CLARITY ADopens in a new tab or window randomized trial. Prescribing information for lecanemab includes a boxed warning about potential risks associated with ARIA. Appropriate use recommendationsopens in a new tab or window discuss ways to minimize ARIA risk, as does AAN guidanceopens in a new tab or window.

CLARITY AD showed that lecanemab led to less decline over 18 months on cognitive and functional measures in early Alzheimer's disease but was associated with serious adverse events, including ARIA and infusion reactions.

The primary efficacy endpoint in the core CLARITY AD trial was change on the CDR-SB, a scale that ranges from 0-18 with higher scores indicating worse impairment. From a baseline CDR-SB score of about 3.2, mean worsening at 18 months was 1.21 with lecanemab and 1.66 with placebo, a difference of 0.45 points. All key secondary endpoints were met.

In the core trial, participants were randomized to either 10 mg/kg lecanemab infusion or placebo biweekly. In the open-label extension, all participants received 10 mg/kg lecanemab biweekly.

The extension study also evaluated CLARITY AD participants who had a delayed start (those who switched from placebo to lecanemab after the core trial) and found that amyloid biomarkers improved in 3 months and remained so with continuous treatment.

No new safety signals were observed with continued lecanemab treatment. After the first 6 months, ARIA rates were similar to rates seen with placebo, van Dyck and colleagues reported.

The extension study did not discuss when lecanemab treatment should end. "I don't think we have any definitive evidence about when to discontinue treatment," van Dyck said. "In my experience, in the clinic, that is a decision that physicians are making case-by-case with their patients and families."

Disclosures

Funding for these studies was provided by Eisai.

van Dyck reported being a consultant for Eisai.

Primary Source

American Academy of Neurology

Source Reference: opens in a new tab or windowvan Dyck CH "Lecanemab for the treatment of early Alzheimer's disease: the extension of the efficacy results from CLARITY AD" AAN 2025.


https://www.medpagetoday.com/meetingcoverage/aan/114987

Paige's cancer detection AI gets FDA breakthrough status

 Digital pathology specialist Paige has been awarded breakthrough device status from the FDA for an artificial intelligence tool that can be used to detect cancer across different areas of the body.

Paige PanCancer Detect is designed to help pathologists assess suspicious lesions in multiple tissues and organs on digital pathology slides and, according to the company, this is the first time that breakthrough status has been awarded for an AI-enabled tool capable of identifying both common cancers and rare variants from different anatomic sites.

Digital pathology technologies are coming to the fore in health systems, as having medical imaging data in an electronic format can improve the efficiency of healthcare, making it easier to get second opinions and input from specialists, for example, regardless of where the patient is located. That becomes more important in areas where access to pathologists may be limited.

"As the demand for pathology services continues to grow at a pace faster than the supply of trained pathologists, AI-powered tools like Paige PanCancer Detect are becoming essential in closing this widening gap," said Paige in a statement.

Pathology labs handle highly variable case types, so a multi-tissue application is important for supporting the growing diagnostic workload, according to the company.

Breakthrough device designation can speed up the development of new medical devices, making them available to patients sooner, and is awarded to technology with the potential to provide more effective treatment or diagnosis of life-threatening or irreversibly debilitating diseases or conditions.

At the moment, Paige PanCancer Detect is still in the experimental stage and can only be used for research purposes, rather than diagnosing patients, but Paige is working towards securing FDA approval for clinical use. It has previously received clearance from the FDA for a prostate cancer detection AI known as Paige ProstateDetect.

First introduced in early 2024 with the ability to detect cancer in 17 tissue and organ types, a recent update expanded that tally to 40, including tumours and pre-cancerous lesions affecting the gastrointestinal and genito-urinary tracts, breast, skin, brain, and others.

Dr David Klimstra, co-founder and former chief medical officer at Paige, said the breakthrough designation "demonstrates the significance of AI in transforming cancer diagnostics," adding: "By aiding in the identification of cases with cancer and flagging potential diagnostic discrepancies, Paige PanCancer Detect can help pathologists focus on the most critical cases and reduce time to diagnosis, leading to faster results for patients."

https://pharmaphorum.com/news/paiges-cancer-detection-ai-gets-fda-breakthrough-status

U.S. envoy says Hezbollah must be disarmed 'as soon as possible'

 U.S. envoy Morgan Ortagus said in an interview broadcast on Sunday that Hezbollah and other armed groups should be disarmed "as soon as possible" and that Lebanese troops were expected to do the job.

Ortagus spoke to Lebanese broadcaster LBCI at the end of a three-day visit to Beirut, where she met with Lebanese President Joseph Aoun, Prime Minister Nawaf Salam, Speaker of Parliament Nabih Berri and other officials and political representatives.

Her visit followed several weeks of intensifying Israeli air strikes on Lebanon targeting members of Iran-backed Hezbollah and the group's weapons depots, including two strikes on Beirut's southern suburbs, and rocket fire from Lebanon onto Israel. Hezbollah denied any role in the rocket attacks.

The exchange of fire tested an already shaky ceasefire that ended a year-long war between Israel and Hezbollah, and calls for the disarmament of armed groups across the country.

"It's clear that Hezbollah has to be disarmed and it's clear that Israel is not going to accept terrorists shooting at them, into their country, and that's a position we understand," Ortagus said.

"We continue to press on this government to fully fulfill the cessation of hostilities and that includes disarming Hezbollah and all militias," she said.

Asked whether the U.S. had set a timeline for the disarmament to take place, Ortagus said, "As soon as possible."

"There's not necessarily a timetable so to speak, but we know that the sooner that the LAF (Lebanese Armed Forces) is able to meet these goals and disarm all militias in the state, the sooner the Lebanese people can be free," she said.

The ceasefire agreement calls for Lebanese troops to dismantle armed groups' military positions and confiscate unauthorised arms "starting with" south Lebanon. The army has destroyed hundreds of weapons caches in south Lebanon since the deal was agreed in November, security sources have told Reuters.

Hezbollah has long rejected attempts to disarm it. It says the ceasefire applies exclusively to southern Lebanon, and not the entire country, and points to Israel's air strikes and continued presence in five hilltop positions in southern Lebanon as major breaches of the truce.

https://www.aol.com/news/u-envoy-says-hezbollah-must-195010069.html

School-age child dies in Texas measles outbreak; Kennedy now calls vaccine best protection

 A second child with measles has died in Texas, state officials said on Sunday (Apr 6), in an outbreak of the childhood disease that has resulted in nearly 500 cases in Texas and has spread across 22 states.

The school-aged child, who was unvaccinated and had no underlying health conditions, died on Thursday in the hospital from measles pulmonary failure, the Texas Department of State Health Services said.

"The child was receiving treatment for complications of measles while hospitalized," Aaron Davis, a spokesperson for UMC Health System in Lubbock, Texas, said in an email.

It is the second death of a child in Texas since the measles outbreak began in late January.

Health and Human Services Secretary Robert F Kennedy Jr, in a post on X, identified the child as 8-year-old Daisy Hildebrand.

Kennedy, who has been an anti-vaccine advocate and previously has said vaccination is a personal choice, on Sunday said vaccines are the best protection against measles.

"The most effective way to prevent the spread of measles is the MMR vaccine," he said in the post on X. He said that as of Sunday there are 642 confirmed cases of measles, 499 of those in Texas.

Kennedy said in his post that he visited Texas to comfort the Hildebrand family after their daughter's death. He added that he got to know the family of the first child in Texas to die in the measles outbreak, Kayley Fehr, "after she passed away in February."

https://www.channelnewsasia.com/world/school-age-child-dies-texas-measles-outbreak-health-chief-kennedy-now-calls-vaccine-best-protection-5048051

Bessent Exposes Zelensky's Lies In Dodging U.S. Minerals Deal

 Treasury Secretary Scott Bessent has accused Ukrainian President Volodymyr Zelensky of repeatedly deceiving the Trump administration about the proposed critical minerals agreement with the United States.

In a candid interview with conservative journalist Tucker Carlson, Bessent alleged that Zelensky “lied to our faces three times” about signing the deal, which would provide U.S. companies with access to Ukraine’s vital strategic minerals."

Bessent explain that Carlson that he flew to Kyiv to sign the agreement with Zelensky—but the Ukrainian leader refused. Instead, Zelensky agreed to sign the deal during a meeting with Vice President JD Vance and Secretary of State Marco Rubio in Munich, Germany, which never occurred. 

“He didn’t sign it there,” Bessent began. “There was a lot of back and forth.”

The following week, they’re beginning to come to the White House,” the Treasury secretary continued. “Then he got to the Oval Office and blew up, which should have been the easiest thing to do in the world.”

There’s a famous photo in the East Wing ballroom of everything laid out on the table to be signed—and it never got signed,” he added.

Bessent explained to Carlson that he believes the deal remains unsigned due to Zelensky receiving misguided advice from his advisors. He emphasized the contrast between the U.S. agreement and the unfavorable "loan-to-buy" arrangements that China has imposed on other countries.

You know who doesn’t sign that deal? Someone with their hand in the till," Bessent remarked, hinting at probable financial wrongdoing. He went on to sharply criticize Zelenskyy’s conduct, branding the Ukrainian leader a ‘vaudevillian’ for his handling of the situation.

"It's a genuine economic partnership,’ the top Trump administration official continued. “We don't make any money unless they make money, and you know who doesn't like that? People with their hand in the till.

The Russians didn't like the look of this deal because they thought it was actually something durable for the U.S. people and the Ukrainian people," he added.

Bessent later told Carlson that Ukraine officials will travel to the U.S. in the coming days to work on the deal. 

*  *  *

https://www.zerohedge.com/political/scott-bessent-exposes-zelenskys-lies-dodging-us-minerals-deal