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Monday, May 1, 2023

Florida oversight board votes to sue Disney

 The local governing board that oversees much of Walt Disney World voted on Monday to sue the company as part of an ongoing political feud fueled by Gov. Ron DeSantis.

The five-person Central Florida Tourism Oversight Board voted unanimously to sue Walt Disney World in state court less than a week after the company filed its own lawsuit against both DeSantis and the board, among a handful of other officials. 

The company sued after the board voted to invalidate an agreement the previous board passed allowing the company to keep control of much of its operations just as DeSantis and his Republican allies were preparing to pass legislation allowing the governor to appoint a new board.

“When I explain the idea that this board is trying to bring new and better ideas to the district, it makes all the sense to all my friends on the right and left,” said board chairman Martin Garcia.

A Disney spokesperson did not return a request for comment.

The fight, which has been going on for more than a year, stems from then-Walt Disney World chief executive Bob Chapek issuing a statement in March 2022 opposing DeSantis-championed legislation banning the discussion of gender identity and sexual orientation in classrooms up until third grade. Opponents branded the bill “Don’t Say Gay.”

The company’s opposition prompted DeSantis to eventually get the GOP-dominated legislature to pass a bill giving DeSantis the power to appoint a new board, which he has since stocked with political supporters.

Walt Disney World sued the company in a Tallahassee-based federal court after the DeSantis-appointed board voted to nullify a development agreement the previous board had agreed to. It was passed with the aim of keeping company operations in the hands of Walt Disney World rather than the DeSantis-appointed board, out of fear the new board would be hostile towards its interests.

Garcia noted that the board’s lawsuit, which is not yet filed, will be in state court in central Florida, which he said is in “our backyard,” a reference to the company filing its lawsuit in Tallahassee.

Board member Ron Peri said he does not like that the board has been portrayed as a political weapon used by DeSantis, or how individual board members have been covered publicly. He specifically referenced a story with an old quote of his that implied he thought drinking tap water could make people gay.

The former pastor, who is the CEO of a Christian ministry focused on outreach to men, was referring to a March CNN article that reported on a since deleted YouTube video where Peri seemed to make the connection between the two.

“So why are there homosexuals today? There are any number of reasons, you know, that are given. Some would say the increase in estrogen in our societies. You know, there’s estrogen in the water from birth control pills. They can’t get it out,” Peri said in January 2022, according to CNN. “The level of testosterone in men broadly in America has declined by 50 points in the past 10 years. You know, and so, maybe that’s a part of it.”

https://www.nbcnews.com/politics/2024-election/oversight-board-votes-sue-disney-fight-ron-desantis-rcna82232

Three-Times-Deported Mexican Who Shot 5 Neighbors Described By Media As "Texas Man"

 by Paul Joseph Watson via Summit News,

A three times deported Mexican national who allegedly shot and killed five of his neighbors, including a child, is being described by the media as a “Texas man”.

Twitter/Bill Melugin

Drone-Escorted Buses Evacuate Hundreds Of Americans To Port Sudan

 Following expressions of shock and disgust by Americans disappointed that the Biden administration wasn't facilitating their evacuation from war-torn Sudan, two bus convoys ferried Americans to the safer city of Port Sudan on the country's Red Sea coast over the weekend. 

In the first convoy, buses traveled more than 500 miles under the protection of armed U.S. drones. However, from Port Sudan, Americans are left to find tickets on boats making the voyage across the Red Sea to the Saudi city of Jeddah -- a trip that, by ferry, takes about 12 hours.

Conformis wins FDA nod for knee replacement system

 

Conformis (CFMS) added ~11% on Monday after a federal registry indicated the FDA's 510(k) clearance for a knee replacement system

Vyne Picks Immuno-Inflammatory Candidate for Development

 Preclinical studies suggest VYN202 has the potential to be the most potent and selective BET inhibitor in development

VYN202 has demonstrated a potent anti-inflammatory and anti-fibrotic effect in multiple validated preclinical models of autoimmune disease

IND-enabling studies are ongoing in anticipation of an IND filing by year-end

 VYNE Therapeutics Inc. (Nasdaq: VYNE) (“VYNE” or the “Company”), a clinical-stage biopharmaceutical company developing proprietary, innovative and differentiated therapies for the treatment of immuno-inflammatory conditions, today announced the selection of a development candidate for its oral BD2-selective bromodomain and extra-terminal (“BET”) inhibitor program, VYN202, for the treatment of immuno-inflammatory conditions. The lead candidate was selected by VYNE from a library of BD2-selective BET inhibitors that VYNE exclusively licensed from Tay Therapeutics following the receipt of a robust package of preclinical data, including encouraging results from well-validated animal models in various autoimmune disorders. VYNE also obtained rights to several other BD2-selective BET inhibitor compounds with attractive molecular profiles that the Company may develop, at its discretion, in the future.

https://finance.yahoo.com/news/vyne-therapeutics-announces-selection-development-120000411.html

Lordstown receives letter from Foxconn alleging agreement breach

 Lordstown Motors Corp said on Monday that Taiwan's Foxconn had alleged that the electric-vehicle startup was in breach of their investment agreement following a Nasdaq delisting notice.

The U.S. company said it was in talks with Foxconn to seek a resolution.

https://finance.yahoo.com/news/lordstown-receives-letter-foxconn-alleging-132559034.html

Aptorum in Merger Pact with Universal Sequencing Tech

 Aptorum Group Limited (Nasdaq: APM, Euronext Paris: APM) ("Aptorum Group" or "Company"), today announced that its wholly owned subsidiary Aptorum Therapeutics Limited ("ATL") has entered into a non-binding Letter of Intent and Term Sheet ("Term Sheet") to merge ("Transaction") its 100% subsidiary, Paths Innovation Limited and its underlying business (collectively "PathsDx Group") with Universal Sequencing Technology Corporation ("UST"), a San Diego and Boston based US company dedicated to the development and commercialization of advanced proprietary DNA sequencing technologies. Paths Innovation Limited currently holds, through its majority owned subsidiary Paths Diagnostics Pte. Limited, the PathsDx technology – a liquid biopsy NGS based technology for the diagnostics of infectious diseases. As consideration of the Transaction upon closing, ATL will become a shareholder of the combined company.

The Transaction and other ancillary distributions, where relevant, are subject to, among other matters, the execution of a mutually agreeable definitive agreement (the "Definitive Agreement"), completion of due diligence and subject to several conditions including, but not limited to, director and shareholder approvals. The relevant Term Sheet has been filed under a 6-K by the Company.

About Universal Sequencing Technology Corporation

Universal Sequencing Technology Corporation (UST) is a biotechnology company based in San Diego and Boston, established by a group of NGS veterans, dedicated in the development and commercialization of advanced DNA sequencing technologies. UST’s TELL-SeqTM linked read library technology enables short read NGS platforms, such as Illumina sequencers, to produce super long read results without a long read sequencer. A sequencing ready Illumina library can be prepared in 3 hours in a PCR tube, simple, fast and economic. It requires ultra-low DNA input, only 3-5ng for human genomes and 0.1-0.5ng for microbial genomes or target panels. With UST TELL-Seq library and a short read sequencer, one can do many previously incapable or difficult to do applications, such as de novo sequencing (microbe/animal/insect/plant), metagenomics (ID of new species and variants in microbiomes), whole genome or target phasing, detection of complicated SVs associated with genetic/rare diseases and cancers, genome-wide analysis of meiotic recombination, etc.. UST’s AmpliDropTM single cell technology offers users a fast and affordable but accurate single cell analysis tool capable of multiomics, isoform detection, and other advantages. Currently, UST has filed a total of 25 PCT patent applications covering linked read NGS library preparation, single cell sequencing and groundbreaking nano-sequencing technologies. UST is poised to lead the next wave of DNA sequencing.