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Monday, April 27, 2026

Thermo Fisher Scientific sells microbiology business for $1B to European private equity

 Thermo Fisher Scientific is shedding its microbiology business to private equity firm Astorg nearly a year after initial rumors of a sale surfaced.

The deal is worth $1.075 billion, consisting of cash and a $50 million seller note, according to an April 27 release.

The unit sells antimicrobial susceptibility testing and culture media solutions for clinical, pharma and food safety testing.

It generated $645 million in revenue in 2025 as part of the medtech giant’s Specialty Diagnostics segment. Rumors of a potential sale first surfaced last June.

Astorg told Fierce Medtech in a statement: “Through the transaction, Thermo Fisher’s microbiology business will become an independent, privately owned platform, backed by Astorg.”

The firm added that it “will partner closely with management” to “further scale the business, with a clear focus on accelerating growth and enhancing operational performance.”

The standalone unit has about 2,400 employees and operates 13 manufacturing and R&D sites globally.

Astorg noted in a release, however, that the market for the unit “is underpinned by structural tailwinds, including infection complexity, increasingly stringent food safety standards, and growing quality control requirements across the pharmaceutical industry,” which it said “reinforces the role of microbiology testing in safeguarding public health.”

The deal will be dilutive to adjusted earnings per share by $0.15 for Thermo Fisher in the first full year after closing, the company said, adding that it would provide more details on the impact in the second quarter.

The announcement comes less than a week after Thermo Fisher reported “a strong start to the year,” buoyed by strong first-quarter demand from its pharma and biotech customers, investment in new technologies and the closing of its $9 billion acquisition of clinical trial data company Clario.

First-quarter revenue rose 6% to $11.01 billion. The company also said on an April 23 call with investors that the situation in the Middle East is expected to create “some modest level of inflationary pressure.”

https://www.fiercebiotech.com/medtech/thermo-fisher-scientific-sells-microbiology-biz-1b-european-equity-firm

Neuropsychiatric therapeutics Seaport Therapeutics sets terms for $201 million IPO, pricing this week

 Seaport Therapeutics, a Phase 2 biotech developing therapies for neuropsychiatric indications, announced terms for its IPO on Monday.


The Boston, MA-based company plans to raise $201 million by offering 11.8 million shares at a price range of $16 to $18. General Atlantic intends to purchase $50 million worth of shares in the offering (25% of the deal).

Seaport Therapeutics is a clinical-stage biotechnology company developing oral therapies for neuropsychiatric disorders, including depression, anxiety, and other central nervous system conditions. The company uses its proprietary Glyph platform, a lymphatic-targeting prodrug technology designed to improve oral bioavailability and reduce first-pass metabolism, to reformulate clinically validated mechanisms into differentiated product candidates. Its lead programs include GlyphAllo in Phase 2b for major depressive disorder and GlyphAgo in Phase 1 for generalized anxiety disorder, with additional preclinical candidates targeting depressive and related CNS disorders.

Seaport Therapeutics was founded in 2024. It plans to list on the Nasdaq under the symbol SPTX. Goldman Sachs, J.P. Morgan, Leerink Partners, Citi, and Stifel are the joint bookrunners on the deal. It is expected to price the week of April 27, 2026.

Post-Nasdaq direct listing profit-taking and dilution concerns drive LABT drop

 


Lakewood-Amedex Biotherapeutics direct listed on Nasdaq under LABT on April 23, 2026, sparking intense retail hype and viral interest on platforms like StockTwits. Shares opened around $8, surged intraday toward $9–14 levels with heavy volume, closed at $8.65 (+8%), then fell 15% to $7.35 on April 24 amid over 5 million shares traded. By April 27, the stock opened at $5.75 and closed at $5.64 (down ~23% from April 24 close, aligning with the reported -21.22% move). This reversal reflects fading momentum in a pre-revenue clinical-stage biotech with no new clinical data, earnings, or positive announcements. The company’s lead Bisphosphocin candidate (Nu-3 gel for infected diabetic foot ulcers) is advancing toward a Phase 2a trial later in 2026, but the direct listing raised no new capital. Reports highlighted an impending cash crunch and high likelihood of future equity raises that would dilute shareholders, prompting selling from registered resale shares (noted in the April 23 424B4 filing covering ~4.7 million shares) and profit-taking after the initial pop. No specific negative news (e.g., trial results or regulatory issues) emerged; the move is a classic post-hype correction in a speculative micro-cap name.


https://finviz.com/quote.ashx?t=LABT&p=d

Compass tovecimig improves progression-free but not overall survival in Phase 2/3 biliary tract cancer

 

Compass Therapeutics' tovecimig improves progression-free but not overall survival in Phase 2/3 biliary tract cancer trial

  • Company plans FDA meeting ahead of a BLA submission based on COMPANION-002 biliary tract cancer data.

Oruka's ORKA-001 shows positive Week 16 interim Phase 2a EVERLAST-A psoriasis data

 Oruka's ORKA-001 shows positive Week 16 interim Phase 2a EVERLAST-A data in moderate-to-severe plaque psoriasis, 63.5% achieve PASI 100, supports once-yearly dosing

https://finviz.com/quote.ashx?t=ORKA&p=d

Veradermics' VDPHL01 Phase 2/3 Part A data show strong hair-growth efficacy

 

Veradermics' VDPHL01 Phase 2/3 Part A data show strong hair-growth efficacy, no treatment-related cardiovascular events in male pattern hair loss

  • VDPHL01 met all primary and key secondary endpoints with robust hair growth and favorable safety in Study 302 Part A.

Sagimet Biosciences prices $175M underwritten Series A stock offering at $6 to fund acne Phase 3

 

Sagimet Biosciences prices $175M underwritten Series A stock offering at $6 to fund acne Phase 3 trial, pipeline

  • Offering comprises 29.17 million shares of Series A common stock priced at $6.00 per share.
  • Company will prioritize dermatology programs and halt MASH development until non-dilutive funding is secured.
  • Plans a U.S. Phase 3 denifanstat acne trial in 2H 2026.