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Tuesday, September 15, 2026

BioNTech updated Phase 3 shows gotistobart improved lung cancer overall survival

 

BioNTech reports updated Phase 3 PRESERVE-003 data showing CTLA-4 antibody gotistobart improved overall survival to 18.5 vs 10 months with docetaxel

  • Updated Phase 3 PRESERVE-003 stage 1 trial evaluated gotistobart (BNT316/ONC-392) versus docetaxel in previously treated squamous NSCLC
  • Gotistobart showed manageable safety profile in the updated Phase 3 PRESERVE-003 stage 1 data

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