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Friday, May 1, 2026

Esperion Therapeutics to be acquired by ARCHIMED for $3.16 per share cash plus up-to-$100M CVRs

 


  • Transaction values Esperion at up to approximately $1.1B including cash consideration and contingent value rights.
  • CVR pays $40M if 2027 U.S. Nexletol/Nexlizet net sales exceed $350M under the definitive agreement.
  • Additional $60M CVR payment triggered if Enbumyst U.S. sales top $160M by the end of 2030.

Cue raises $30M to fund clinical pipeline and Ascendant-221

 

Cue Biopharma raises $30M in PIPE financing at effective $11.00 per unit to fund clinical pipeline and Ascendant-221

  • PIPE consists of pre-funded warrants and common stock warrants, with proceeds funding clinical programs and Ascendant-221 acquisition efforts.
  • Cue Biopharma licenses Ascendant-221 anti-IgE antibody from Ascendant Health Sciences, obtaining global rights outside Greater China.
  • Financial terms include $15M upfront payment and up to $676.5M in milestone-based payments.
  • Agreement provides an exclusive license to Ascendant-221 plus royalties payable to Ascendant Health Sciences on global sales.
  • Cue and Ascendant Health Sciences plan a global Phase 2b trial of Ascendant-221 in food allergy.
  • Cue Biopharma appoints Shao-Lee Lin, M.D., Ph.D., as CEO, president and board director.
  • Lin succeeds interim CEO Lucinda Warren and is tasked with leading Cue Biopharma’s next phase of growth.

https://breakingthenews.net/Article/Iran-may-have-sent-response-to-US-on-Thursday/66201230

NY set to pass most extreme sanctuary policies as Hochul, Albany Dems near anti-ICE deal

 New York is set to pass its most extreme sanctuary policies yet – as Gov. Kathy Hochul and Albany Democrats hone in on a deal that could impose sweeping bans on cooperation between local law enforcement and ICE.

Assembly Speaker Carl Heastie (D-Bronx) confirmed “95%” of an anti-ICE immigration package has been agreed upon between Hochul and state legislators as part of ongoing state budget talks – including etching New York’s first statewide sanctuary law restricting how law enforcement can interact with immigration authorities.

“I think we all want to deal with the aggressiveness, or the over-aggressiveness, let’s say, of ICE. But we also understand that there should always be due process,” Heastie told reporters Wednesday.

Gov. Kathy Hochul and legislative leaders are forging ahead with legislation to put statewide sanctuary policies on New York’s books for the first time.Stephen Yang for NY Post

Narrow, but still crucial, details about how the law would function are still being hammered out.

Hochul recently revealed that she had agreed with the legislature’s request to ramp up her initial anti-ICE proposal, which she had released in January amid heightened fury against President Trump’s immigration crackdown in Minneapolis.

“I want to say that ICE has no reason to be involved in any civil enforcement,” Hochul said last week.

Hochul’s original proposal had included:

  • Banning local governments, like Nassau County, from signing formal “287-g” agreements with ICE to deputize officers and keep detainees in local jails on federal immigration charges.
  • An experimental new legal tool aimed at  giving New Yorkers the ability to sue federal agents in state court for a violation of their constitutional rights.
  • Restricting access to ICE from “sensitive” locations like schools, hospitals and churches.

Since then, the legislature has largely bullied the governor into adding:

Assembly Speaker Carl Heastie (D-Bronx) told reporters an immigration package was “95%” agreed upon, Wednesday.Gabriella Bass
  • Explicit “sanctuary” protections barring local law enforcement from communicating with federal immigration authorities unless they suspect there’s probable cause someone committed a misdemeanor or felony.
  • Many new additional “sensitive” locations to her list, including virtually all public spaces like parks and allowing private businesses to refuse entry to federal agents.
  • Barring ICE agents from wearing masks.
ICE agents would be barred from wearing masks in New York, under the newest iteration of the proposal, Hochul revealed earlier this month.Adam Gray for New York Post

Albany Dems, however, quickly panned the part of Hochul’s plan allowing local cops to contact ICE in cases with probable cause — and it appears she might be backing down.

“That definitely has been out,” Heastie said Wednesday.

Critics — including the elected sheriffs she wants to restrict from working with ICE — have blasted Hochul for caving to the left, claiming she hasn’t engaged with them in crafting her proposal.

Local law enforcement, including the New York State Sheriffs Association, is opposed to the new immigration measures.Getty Images

“The proposed ban on communicating or cooperating with an important unit of federal law enforcement would be a huge step backward and would be detrimental to the safety of the public in areas way beyond immigration issues,” the New York State Sheriffs’ Association wrote in a statement this week.

Turning New York’s sanctuary policy into law could create confusing grey areas and would harm the progress made after the 9/11 terror attacks to encourage branches of law enforcement to be less “siloed” and collaborate more, critics argued.

Hochul still maintains that federal law enforcement will still be able to go after hardcore criminals like human traffickers and drug rings.

“We’ll work with DEA. We’ll work with FBI. We always have,” she stressed.

https://nypost.com/2026/04/30/us-news/ny-set-to-pass-most-extreme-sanctuary-policies-as-hochul-albany-dems-near-anti-ice-deal/

Iran may send revised proposal on Friday after Trump rejection - CNN

Iran is expected to deliver a revised peace proposal by Friday after US President Donald Trump rejected an earlier version, CNN reported citing Pakistani mediators.

US Navy deploys AI to detect Iranian mines - Reuters

 

The US Navy is expanding use of artificial intelligence to detect Iranian naval mines in the Strait of Hormuz, aiming to speed up clearance operations, Reuters reported.

A contract worth up to $100 million with Domino Data Lab will allow underwater drones to identify new types of mines within days rather than months. A company executive said the shift marks a move from ship-based mine hunting to AI-driven systems, as the US seeks to secure a key global shipping route.

https://www.iranintl.com/en/liveblog/202604294038

Iran embassy rejects role in UK violence

 

Iran’s embassy in London dismissed reports linking Tehran to violent incidents in Britain as "unfounded," saying authorities reject such accusations.

The embassy said the Islamic Republic condemns “terrorism” in all forms and described itself as "a victim of such acts," adding it remains "committed to confronting extremism."

https://www.iranintl.com/en/liveblog/202604294038