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Monday, September 21, 2026

Positive CUE-221 Phase 2 CSU results lift Cue Biopharma in pre-market

 


  • Cue Biopharma issued Sunday 6 AM ET GlobeNewswire release on CUE-221 Phase 2 CSU data.
  • Primary endpoint of complete hive resolution at week 12 met at all three doses versus placebo.
  • Highest 4 mg/kg dose showed 54% HSS7=0 and 46% UAS7=0 complete response versus 11% placebo.
  • Favorable safety with no treatment-related SAEs; durability seen 12 weeks off therapy.
  • Results support advancing to Phase 2b/3 CSU study and food allergy development.
  • Announcement came after Friday close, so first reaction is Monday pre-market.
  • B. Riley Buy initiation Friday with $83 target noted CUE-221 as near-term catalyst.
  • Company hosts 8 AM ET conference call today to discuss the data.

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