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Thursday, September 24, 2026

Merck Wnt DME trial success lifts Surrozen pre-market on read-through

 


  • Merck at 6:45 AM ET said remigromig met BRUNELLO Phase 2b/3 primary endpoint in DME.
  • Both doses were non-inferior to ranibizumab on 52-week best-corrected visual acuity.
  • Higher PDR, vitreous hemorrhage and dropouts versus control noted in the Wnt monotherapy.
  • Traders viewed the Wnt validation plus safety caveats as bullish for SRZN's VEGF-combo SZN-8141.
  • Biotech posts on X highlighted the mechanism success as a positive read-through for Surrozen.
  • No Surrozen press release, 8-K or analyst note appeared after the prior close.
  • The 62% gap far exceeds the stock's 7% average daily range, matching the catalyst scale.

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